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Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma.
Takata K, Chong LC, Ennishi D, Aoki T, Li MY, Thakur A, Healy S, Viganò E, Dao T, Kwon D, Duns G, Nielsen JS, Ben-Neriah S, Tse E, Hung SS, Boyle M, Mun SS, Bourne CM, Woolcock B, Telenius A, Kishida M, Rai S, Zhang AW, Bashashati A, Saberi S, D'Antonio G, Nelson BH, Shah SP, Hoodless PA, Melnick AM, Gascoyne RD, Connors JM, Scheinberg DA, Béguelin W, Scott DW, Steidl C. Takata K, et al. Among authors: bourne cm. J Clin Invest. 2022 May 16;132(10):e145343. doi: 10.1172/JCI145343. J Clin Invest. 2022. PMID: 35380993 Free PMC article.
Targeted Cellular Micropharmacies: Cells Engineered for Localized Drug Delivery.
Gardner TJ, Bourne CM, Dacek MM, Kurtz K, Malviya M, Peraro L, Silberman PC, Vogt KC, Unti MJ, Brentjens R, Scheinberg D. Gardner TJ, et al. Among authors: bourne cm. Cancers (Basel). 2020 Aug 5;12(8):2175. doi: 10.3390/cancers12082175. Cancers (Basel). 2020. PMID: 32764348 Free PMC article. Review.
Engineering CAR-T cells to activate small-molecule drugs in situ.
Gardner TJ, Lee JP, Bourne CM, Wijewarnasuriya D, Kinarivala N, Kurtz KG, Corless BC, Dacek MM, Chang AY, Mo G, Nguyen KM, Brentjens RJ, Tan DS, Scheinberg DA. Gardner TJ, et al. Among authors: bourne cm. Nat Chem Biol. 2022 Feb;18(2):216-225. doi: 10.1038/s41589-021-00932-1. Epub 2021 Dec 30. Nat Chem Biol. 2022. PMID: 34969970 Free PMC article.
Host Interactions with Engineered T-cell Micropharmacies.
Bourne CM, Wallisch P, Dacek MM, Gardner TJ, Pierre S, Vogt K, Corless BC, Bah MA, Romero-Pichardo JE, Charles A, Kurtz KG, Tan DS, Scheinberg DA. Bourne CM, et al. Cancer Immunol Res. 2023 Sep 1;11(9):1253-1265. doi: 10.1158/2326-6066.CIR-22-0879. Cancer Immunol Res. 2023. PMID: 37379366 Free PMC article.
18 results