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HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration.
Fitsialos G, Bourget I, Augier S, Ginouvès A, Rezzonico R, Odorisio T, Cianfarani F, Virolle T, Pouysségur J, Meneguzzi G, Berra E, Ponzio G, Buscà R. Fitsialos G, et al. Among authors: bourget i. J Cell Sci. 2008 Sep 15;121(Pt 18):2992-3001. doi: 10.1242/jcs.029256. Epub 2008 Aug 19. J Cell Sci. 2008. PMID: 18713836
LIF mediates proinvasive activation of stromal fibroblasts in cancer.
Albrengues J, Bourget I, Pons C, Butet V, Hofman P, Tartare-Deckert S, Feral CC, Meneguzzi G, Gaggioli C. Albrengues J, et al. Among authors: bourget i. Cell Rep. 2014 Jun 12;7(5):1664-1678. doi: 10.1016/j.celrep.2014.04.036. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857661 Free article.
Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation.
Brahimi-Horn MC, Giuliano S, Saland E, Lacas-Gervais S, Sheiko T, Pelletier J, Bourget I, Bost F, Féral C, Boulter E, Tauc M, Ivan M, Garmy-Susini B, Popa A, Mari B, Sarry JE, Craigen WJ, Pouysségur J, Mazure NM. Brahimi-Horn MC, et al. Among authors: bourget i. Cancer Metab. 2015 Aug 26;3:8. doi: 10.1186/s40170-015-0133-5. eCollection 2015. Cancer Metab. 2015. PMID: 26322231 Free PMC article.
Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells.
Grasset EM, Bertero T, Bozec A, Friard J, Bourget I, Pisano S, Lecacheur M, Maiel M, Bailleux C, Emelyanov A, Ilie M, Hofman P, Meneguzzi G, Duranton C, Bulavin DV, Gaggioli C. Grasset EM, et al. Among authors: bourget i. Cancer Res. 2018 Sep 15;78(18):5229-5242. doi: 10.1158/0008-5472.CAN-18-0601. Epub 2018 Jul 19. Cancer Res. 2018. PMID: 30026329
The Polo-like kinase 1 inhibitor onvansertib represents a relevant treatment for head and neck squamous cell carcinoma resistant to cisplatin and radiotherapy.
Hagege A, Ambrosetti D, Boyer J, Bozec A, Doyen J, Chamorey E, He X, Bourget I, Rousset J, Saada E, Rastoin O, Parola J, Luciano F, Cao Y, Pagès G, Dufies M. Hagege A, et al. Among authors: bourget i. Theranostics. 2021 Sep 21;11(19):9571-9586. doi: 10.7150/thno.61711. eCollection 2021. Theranostics. 2021. PMID: 34646387 Free PMC article.
Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma.
Hagege A, Saada-Bouzid E, Ambrosetti D, Rastoin O, Boyer J, He X, Rousset J, Montemagno C, Doyen J, Pedeutour F, Parola J, Bourget I, Luciano F, Bozec A, Cao Y, Pagès G, Dufies M. Hagege A, et al. Among authors: bourget i. Cell Rep Med. 2022 Sep 20;3(9):100659. doi: 10.1016/j.xcrm.2022.100659. Cell Rep Med. 2022. PMID: 36130479 Free PMC article.
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