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Therapeutics discovery: From bench to first in-human trials.
Al-Hujaily EM, Khatlani T, Alehaideb Z, Ali R, Almuzaini B, Alrfaei BM, Iqbal J, Islam I, Malik S, Marwani BA, Massadeh S, Nehdi A, Alsomaie B, Debasi B, Bushnak I, Noibi S, Hussain S, Wajid WA, Armand JP, Gul S, Oyarzabal J, Rais R, Bountra C, Alaskar A, Knawy BA, Boudjelal M. Al-Hujaily EM, et al. Among authors: bountra c. Biomed Rep. 2018 Mar;8(3):275-282. doi: 10.3892/br.2018.1052. Epub 2018 Jan 31. Biomed Rep. 2018. PMID: 29564125 Free PMC article.
Open innovation in neuroscience research and drug discovery.
Hunter AJ, Lee WH, Bountra C. Hunter AJ, et al. Among authors: bountra c. Brain Neurosci Adv. 2018 Sep 13;2:2398212818799270. doi: 10.1177/2398212818799270. eCollection 2018 Jan-Dec. Brain Neurosci Adv. 2018. PMID: 32166150 Free PMC article. Review.
Open Access Could Transform Drug Discovery: A Case Study of JQ1.
Arshad Z, Smith J, Roberts M, Lee WH, Davies B, Bure K, Hollander GA, Dopson S, Bountra C, Brindley D. Arshad Z, et al. Among authors: bountra c. Expert Opin Drug Discov. 2016;11(3):321-32. doi: 10.1517/17460441.2016.1144587. Expert Opin Drug Discov. 2016. PMID: 26791045 Review.
The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery.
Bradley AR, Echalier A, Fairhead M, Strain-Damerell C, Brennan P, Bullock AN, Burgess-Brown NA, Carpenter EP, Gileadi O, Marsden BD, Lee WH, Yue W, Bountra C, von Delft F. Bradley AR, et al. Among authors: bountra c. Essays Biochem. 2017 Nov 8;61(5):495-503. doi: 10.1042/EBC20170051. Print 2017 Nov 8. Essays Biochem. 2017. PMID: 29118096 Free PMC article. Review.
The structural basis of ZMPSTE24-dependent laminopathies.
Quigley A, Dong YY, Pike AC, Dong L, Shrestha L, Berridge G, Stansfeld PJ, Sansom MS, Edwards AM, Bountra C, von Delft F, Bullock AN, Burgess-Brown NA, Carpenter EP. Quigley A, et al. Among authors: bountra c. Science. 2013 Mar 29;339(6127):1604-7. doi: 10.1126/science.1231513. Science. 2013. PMID: 23539603
21(st) Century Cures Act: An Act of Cure or Diagnosis?
Brindley DA, Arshad Z, Luo D, Dopson S, Hollander G, Frost S, Bountra C, Smith JA. Brindley DA, et al. Among authors: bountra c. Rejuvenation Res. 2015 Aug;18(4):295-8. doi: 10.1089/rej.2015.1757. Rejuvenation Res. 2015. PMID: 26291241 Free PMC article. No abstract available.
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.
Picaud S, Wells C, Felletar I, Brotherton D, Martin S, Savitsky P, Diez-Dacal B, Philpott M, Bountra C, Lingard H, Fedorov O, Müller S, Brennan PE, Knapp S, Filippakopoulos P. Picaud S, et al. Among authors: bountra c. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19754-9. doi: 10.1073/pnas.1310658110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248379 Free PMC article.
121 results