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GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia.
Kim-Muller JY, Song L, LaCarubba Paulhus B, Pashos E, Li X, Rinaldi A, Joaquim S, Stansfield JC, Zhang J, Robertson A, Pang J, Opsahl A, Boucher M, Breen D, Hales K, Sheikh A, Wu Z, Zhang BB. Kim-Muller JY, et al. Among authors: boucher m. Cell Rep. 2023 Jan 31;42(1):111947. doi: 10.1016/j.celrep.2022.111947. Epub 2023 Jan 10. Cell Rep. 2023. PMID: 36640326 Free article.
FGF21 increases water intake, urine output and blood pressure in rats.
Turner T, Chen X, Zahner M, Opsahl A, DeMarco G, Boucher M, Goodwin B, Perreault M. Turner T, et al. Among authors: boucher m. PLoS One. 2018 Aug 14;13(8):e0202182. doi: 10.1371/journal.pone.0202182. eCollection 2018. PLoS One. 2018. PMID: 30106981 Free PMC article.
Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
Ross TT, Crowley C, Kelly KL, Rinaldi A, Beebe DA, Lech MP, Martinez RV, Carvajal-Gonzalez S, Boucher M, Hirenallur-Shanthappa D, Morin J, Opsahl AC, Vargas SR, Bence KK, Pfefferkorn JA, Esler WP. Ross TT, et al. Among authors: boucher m. Cell Mol Gastroenterol Hepatol. 2020;10(4):829-851. doi: 10.1016/j.jcmgh.2020.06.001. Epub 2020 Jun 9. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32526482 Free PMC article.
Characterization of cachexia in the human fibrosarcoma HT-1080 mouse tumour model.
Bernardo B, Joaquim S, Garren J, Boucher M, Houle C, LaCarubba B, Qiao S, Wu Z, Esquejo RM, Peloquin M, Kim H, Breen DM. Bernardo B, et al. Among authors: boucher m. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1813-1829. doi: 10.1002/jcsm.12618. Epub 2020 Sep 13. J Cachexia Sarcopenia Muscle. 2020. PMID: 32924335 Free PMC article.
Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension.
Song L, Chen X, Swanson TA, LaViolette B, Pang J, Cunio T, Nagle MW, Asano S, Hales K, Shipstone A, Sobon H, Al-Harthy SD, Ahn Y, Kreuser S, Robertson A, Ritenour C, Voigt F, Boucher M, Sun F, Sessa WC, Roth Flach RJ. Song L, et al. Among authors: boucher m. Elife. 2020 Nov 17;9:e58376. doi: 10.7554/eLife.58376. Elife. 2020. PMID: 33200983 Free PMC article.
ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials.
Calle RA, Amin NB, Carvajal-Gonzalez S, Ross TT, Bergman A, Aggarwal S, Crowley C, Rinaldi A, Mancuso J, Aggarwal N, Somayaji V, Inglot M, Tuthill TA, Kou K, Boucher M, Tesz G, Dullea R, Bence KK, Kim AM, Pfefferkorn JA, Esler WP. Calle RA, et al. Among authors: boucher m. Nat Med. 2021 Oct;27(10):1836-1848. doi: 10.1038/s41591-021-01489-1. Epub 2021 Oct 11. Nat Med. 2021. PMID: 34635855 Clinical Trial.
GPAT1 Deficiency in Mice Modulates NASH Progression in a Model-Dependent Manner.
Smith KR, Wang W, Miller MR, Boucher M, Reynold JE, Daurio NA, Li D, Hirenallur-Shanthappa D, Ahn Y, Beebe DA, Kelly KL, Ross TT, Bence KK, Wan M. Smith KR, et al. Among authors: boucher m. Cell Mol Gastroenterol Hepatol. 2024;17(2):279-291. doi: 10.1016/j.jcmgh.2023.10.002. Epub 2023 Oct 14. Cell Mol Gastroenterol Hepatol. 2024. PMID: 37844795 Free PMC article.
607 results