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Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.
Napolitano V, Dabrowska A, Schorpp K, Mourão A, Barreto-Duran E, Benedyk M, Botwina P, Brandner S, Bostock M, Chykunova Y, Czarna A, Dubin G, Fröhlich T, Hölscher M, Jedrysik M, Matsuda A, Owczarek K, Pachota M, Plettenburg O, Potempa J, Rothenaigner I, Schlauderer F, Slysz K, Szczepanski A, Greve-Isdahl Mohn K, Blomberg B, Sattler M, Hadian K, Popowicz GM, Pyrc K. Napolitano V, et al. Among authors: bostock m. Cell Chem Biol. 2022 May 19;29(5):774-784.e8. doi: 10.1016/j.chembiol.2021.11.006. Epub 2022 Jan 11. Cell Chem Biol. 2022. PMID: 35021060 Free PMC article.
Paramagnetic NMR in drug discovery.
Softley CA, Bostock MJ, Popowicz GM, Sattler M. Softley CA, et al. Among authors: bostock mj. J Biomol NMR. 2020 Jul;74(6-7):287-309. doi: 10.1007/s10858-020-00322-0. Epub 2020 Jun 10. J Biomol NMR. 2020. PMID: 32524233 Free PMC article. Review.
Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia.
Zak KM, Bostock MJ, Waligorska I, Thøgersen IB, Enghild JJ, Popowicz GM, Grudnik P, Potempa J, Ksiazek M. Zak KM, et al. Among authors: bostock mj. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1267-1281. doi: 10.1080/14756366.2021.1937619. J Enzyme Inhib Med Chem. 2021. PMID: 34210221 Free PMC article.
Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase.
Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM. Softley CA, et al. Among authors: bostock mj. Antimicrob Agents Chemother. 2020 May 21;64(6):e00123-20. doi: 10.1128/AAC.00123-20. Print 2020 May 21. Antimicrob Agents Chemother. 2020. PMID: 32205343 Free PMC article.
Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase".
Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM. Softley CA, et al. Among authors: bostock mj. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e01077-20. doi: 10.1128/AAC.01077-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32576598 Free PMC article. No abstract available.
Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler.
Liwocha J, Krist DT, van der Heden van Noort GJ, Hansen FM, Truong VH, Karayel O, Purser N, Houston D, Burton N, Bostock MJ, Sattler M, Mann M, Harrison JS, Kleiger G, Ovaa H, Schulman BA. Liwocha J, et al. Among authors: bostock mj. Nat Chem Biol. 2021 Mar;17(3):272-279. doi: 10.1038/s41589-020-00696-0. Epub 2020 Dec 7. Nat Chem Biol. 2021. PMID: 33288957 Free PMC article.
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