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LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.
Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T. Proteau S, et al. Among authors: bost f. EMBO Mol Med. 2023 Dec 7;15(12):e17719. doi: 10.15252/emmm.202317719. Epub 2023 Nov 15. EMBO Mol Med. 2023. PMID: 37966164 Free PMC article.
[Medulloblastoma: The latest major advances].
Contenti J, Bost F, Mazure NM. Contenti J, et al. Among authors: bost f. Bull Cancer. 2023 Apr;110(4):412-423. doi: 10.1016/j.bulcan.2023.02.002. Epub 2023 Feb 21. Bull Cancer. 2023. PMID: 36822958 Review. French.
Cell Plasticity in a Mouse Model of Benign Prostate Hyperplasia Drives Amplification of Androgen-Independent Epithelial Cell Populations Sensitive to Antioxidant Therapy.
Dos Santos L, Carbone F, Pacreau E, Diarra S, Luka M, Pigat N, Baures M, Navarro E, Anract J, Barry Delongchamps N, Cagnard N, Bost F, Nemazanyy I, Petitjean O, Hamaï A, Ménager M, Palea S, Guidotti JE, Goffin V. Dos Santos L, et al. Among authors: bost f. Am J Pathol. 2024 Jan;194(1):30-51. doi: 10.1016/j.ajpath.2023.09.010. Epub 2023 Oct 10. Am J Pathol. 2024. PMID: 37827216
Nanoblades allow high-level genome editing in murine and human organoids.
Tiroille V, Krug A, Bokobza E, Kahi M, Bulcaen M, Ensinck MM, Geurts MH, Hendriks D, Vermeulen F, Larbret F, Gutierrez-Guerrero A, Chen Y, Van Zundert I, Rocha S, Rios AC, Medaer L, Gijsbers R, Mangeot PE, Clevers H, Carlon MS, Bost F, Verhoeyen E. Tiroille V, et al. Among authors: bost f. Mol Ther Nucleic Acids. 2023 Jun 8;33:57-74. doi: 10.1016/j.omtn.2023.06.004. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37435135 Free PMC article.
The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitntriors.
Muller C, Lacroix-Malgras V, Kluza J, Laine W, Güler Y, Bost F, Boisbrun M, Mazerbourg S, Flament S. Muller C, et al. Among authors: bost f. Cancer Cell Int. 2024 Apr 10;24(1):132. doi: 10.1186/s12935-024-03319-z. Cancer Cell Int. 2024. PMID: 38594745 Free PMC article.
HIF-1 inactivation empowers HIF-2 to drive hypoxia adaptation in aggressive forms of medulloblastoma.
Contenti J, Guo Y, Larcher M, Mirabal-Ortega L, Rouleau M, Irondelle M, Tiroille V, Mazzu A, Duranton-Tanneur V, Pedeutour F, Ben-Sahra I, Lago C, Leva G, Tiberi L, Robert G, Pouponnot C, Bost F, Mazure NM. Contenti J, et al. Among authors: bost f. bioRxiv [Preprint]. 2023 Oct 20:2023.10.17.562750. doi: 10.1101/2023.10.17.562750. bioRxiv. 2023. PMID: 37905067 Free PMC article. Preprint.
Persistent organic pollutants promote aggressiveness in prostate cancer.
Buñay J, Kossai M, Damon-Soubeyrant C, De Haze A, Saru JP, Trousson A, de Joussineau C, Bouchareb E, Kocer A, Vialat M, Dallel S, Degoul F, Bost F, Clavel S, Penault-Llorca F, Valli MP, Guy L, Matthews J, Renaud Y, Ittmann M, Jones J, Morel L, Lobaccaro JM, Baron S. Buñay J, et al. Among authors: bost f. Oncogene. 2023 Sep;42(38):2854-2867. doi: 10.1038/s41388-023-02788-2. Epub 2023 Aug 17. Oncogene. 2023. PMID: 37587334
126 results