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Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells.
Rodriguez C, Araujo Furlan CL, Tosello Boari J, Bossio SN, Boccardo S, Fozzatti L, Canale FP, Beccaria CG, Nuñez NG, Ceschin DG, Piaggio E, Gruppi A, Montes CL, Acosta Rodríguez EV. Rodriguez C, et al. Among authors: bossio sn. Oncoimmunology. 2023 Oct 5;12(1):2261326. doi: 10.1080/2162402X.2023.2261326. eCollection 2023. Oncoimmunology. 2023. PMID: 37808403 Free PMC article.
COVID-19 patients display changes in lymphocyte subsets with a higher frequency of dysfunctional CD8lo T cells associated with disease severity.
Onofrio LI, Marin C, Dutto J, Brugo MB, Baigorri RE, Bossio SN, Quiróz JN, Almada L, Ruiz Moreno F, Olivera C, Silvera-Ruiz SM, Ponce NE, Icely PA, Amezcua Vesely MC, Fozzatti L, Rodríguez-Galán MC, Stempin CC, Cervi L; ImmunoCovid-CBA; Maletto BA, Acosta Rodríguez EV, Bertone M, Abiega CD, Escudero D, Kahn A, Caeiro JP, Maccioni M, Motrán CC, Gruppi A, Sotomayor CE, Chiapello LS, Montes CL. Onofrio LI, et al. Among authors: bossio sn. Front Immunol. 2023 Sep 21;14:1223730. doi: 10.3389/fimmu.2023.1223730. eCollection 2023. Front Immunol. 2023. PMID: 37809093 Free PMC article.
CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade.
Bossio SN, Abrate C, Tosello Boari J, Rodriguez C, Canale FP, Ramello MC, Brunotto V, Richer W, Rocha D, Sedlik C, Vincent-Salomon A, Borcoman E, Del Castillo A, Gruppi A, Fernandez E, Acosta Rodríguez EV, Piaggio E, Montes CL. Bossio SN, et al. Oncoimmunology. 2023 Aug 18;12(1):2246319. doi: 10.1080/2162402X.2023.2246319. eCollection 2023. Oncoimmunology. 2023. PMID: 37885970 Free PMC article.
Polyfunctional KLRG-1+CD57+ Senescent CD4+ T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients.
Ramello MC, Núñez NG, Tosello Boari J, Bossio SN, Canale FP, Abrate C, Ponce N, Del Castillo A, Ledesma M, Viel S, Richer W, Sedlik C, Tiraboschi C, Muñoz M, Compagno D, Gruppi A, Acosta Rodríguez EV, Piaggio E, Montes CL. Ramello MC, et al. Among authors: bossio sn. Front Immunol. 2021 Jul 27;12:713132. doi: 10.3389/fimmu.2021.713132. eCollection 2021. Front Immunol. 2021. PMID: 34386013 Free PMC article.
B cells from Patients with Rheumatoid Arthritis Show Conserved CD39-Mediated Regulatory Function and increased CD39 Expression After Positive Response to Therapy.
Zacca ER, Amezcua Vesely MC, Ferrero PV, Acosta CDV, Ponce NE, Bossio SN, Mussano E, Onetti L, Cadile I, Acosta Rodríguez EV, Montes CL, Gruppi A. Zacca ER, et al. Among authors: bossio sn. J Mol Biol. 2021 Jan 8;433(1):166687. doi: 10.1016/j.jmb.2020.10.021. Epub 2020 Oct 22. J Mol Biol. 2021. PMID: 33098857 Free PMC article.
CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells.
Canale FP, Ramello MC, Núñez N, Araujo Furlan CL, Bossio SN, Gorosito Serrán M, Tosello Boari J, Del Castillo A, Ledesma M, Sedlik C, Piaggio E, Gruppi A, Acosta Rodríguez EA, Montes CL. Canale FP, et al. Among authors: bossio sn. Cancer Res. 2018 Jan 1;78(1):115-128. doi: 10.1158/0008-5472.CAN-16-2684. Epub 2017 Oct 24. Cancer Res. 2018. PMID: 29066514