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Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: bosmann m. Nature. 2023 Mar;615(7950):143-150. doi: 10.1038/s41586-023-05697-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36630998
SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. Huang J, et al. Among authors: bosmann m. Cell Stem Cell. 2020 Dec 3;27(6):962-973.e7. doi: 10.1016/j.stem.2020.09.013. Epub 2020 Sep 18. Cell Stem Cell. 2020. PMID: 32979316 Free PMC article.
Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression.
Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz K, Ericsson M, Huber BR, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Kurnick S, Bosmann M, Saeed M, Balasuriya U, Douam F, Crossland N. Carossino M, et al. Among authors: bosmann m. bioRxiv [Preprint]. 2021 Sep 23:2021.01.13.425144. doi: 10.1101/2021.01.13.425144. bioRxiv. 2021. PMID: 33469581 Free PMC article. Updated. Preprint.
Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression.
Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Carossino M, et al. Among authors: bosmann m. Viruses. 2022 Mar 5;14(3):535. doi: 10.3390/v14030535. Viruses. 2022. PMID: 35336942 Free PMC article.
Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection.
Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Kenney DJ, et al. Among authors: bosmann m. Cell Rep. 2022 Apr 19;39(3):110714. doi: 10.1016/j.celrep.2022.110714. Epub 2022 Apr 4. Cell Rep. 2022. PMID: 35421379 Free PMC article.
SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. Huang J, et al. Among authors: bosmann m. bioRxiv [Preprint]. 2020 Aug 6:2020.06.30.175695. doi: 10.1101/2020.06.30.175695. bioRxiv. 2020. PMID: 32637964 Free PMC article. Updated. Preprint.
Bacterial polyphosphates interfere with the innate host defense to infection.
Roewe J, Stavrides G, Strueve M, Sharma A, Marini F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C, Morrissey JH, Bosmann M. Roewe J, et al. Among authors: bosmann m. Nat Commun. 2020 Aug 12;11(1):4035. doi: 10.1038/s41467-020-17639-x. Nat Commun. 2020. PMID: 32788578 Free PMC article.
Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.
Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Pontarollo G, et al. Among authors: bosmann m. Nat Metab. 2023 Jul;5(7):1174-1187. doi: 10.1038/s42255-023-00828-5. Epub 2023 Jul 6. Nat Metab. 2023. PMID: 37414930 Free PMC article.
Author Correction: Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.
Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Pontarollo G, et al. Among authors: bosmann m. Nat Metab. 2023 Sep;5(9):1639. doi: 10.1038/s42255-023-00901-z. Nat Metab. 2023. PMID: 37697057 Free PMC article. No abstract available.
77 results