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Crystal structures of the DExH-box RNA helicase DHX9.
Lee YT, Sickmier EA, Grigoriu S, Castro J, Boriack-Sjodin PA. Lee YT, et al. Among authors: boriack sjodin pa. Acta Crystallogr D Struct Biol. 2023 Nov 1;79(Pt 11):980-991. doi: 10.1107/S2059798323007611. Epub 2023 Oct 20. Acta Crystallogr D Struct Biol. 2023. PMID: 37860960 Free PMC article.
A Mass Spectrometric Assay of METTL3/METTL14 Methyltransferase Activity.
Buker SM, Gurard-Levin ZA, Wheeler BD, Scholle MD, Case AW, Hirsch JL, Ribich S, Copeland RA, Boriack-Sjodin PA. Buker SM, et al. Among authors: boriack sjodin pa. SLAS Discov. 2020 Apr;25(4):361-371. doi: 10.1177/2472555219878408. Epub 2019 Oct 4. SLAS Discov. 2020. PMID: 31585521 Free article.
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
Thomenius MJ, Totman J, Harvey D, Mitchell LH, Riera TV, Cosmopoulos K, Grassian AR, Klaus C, Foley M, Admirand EA, Jahic H, Majer C, Wigle T, Jacques SL, Gureasko J, Brach D, Lingaraj T, West K, Smith S, Rioux N, Waters NJ, Tang C, Raimondi A, Munchhof M, Mills JE, Ribich S, Porter Scott M, Kuntz KW, Janzen WP, Moyer M, Smith JJ, Chesworth R, Copeland RA, Boriack-Sjodin PA. Thomenius MJ, et al. Among authors: boriack sjodin pa. PLoS One. 2018 Jun 1;13(6):e0197372. doi: 10.1371/journal.pone.0197372. eCollection 2018. PLoS One. 2018. PMID: 29856759 Free PMC article.
RNA-modifying proteins as anticancer drug targets.
Boriack-Sjodin PA, Ribich S, Copeland RA. Boriack-Sjodin PA, et al. Nat Rev Drug Discov. 2018 Jun;17(6):435-453. doi: 10.1038/nrd.2018.71. Epub 2018 May 18. Nat Rev Drug Discov. 2018. PMID: 29773918 Review.
Identification of a peptide inhibitor for the histone methyltransferase WHSC1.
Morrison MJ, Boriack-Sjodin PA, Swinger KK, Wigle TJ, Sadalge D, Kuntz KW, Scott MP, Janzen WP, Chesworth R, Duncan KW, Harvey DM, Lampe JW, Mitchell LH, Copeland RA. Morrison MJ, et al. Among authors: boriack sjodin pa. PLoS One. 2018 May 9;13(5):e0197082. doi: 10.1371/journal.pone.0197082. eCollection 2018. PLoS One. 2018. PMID: 29742153 Free PMC article.
The Elements of Translational Chemical Biology.
Copeland RA, Boriack-Sjodin PA. Copeland RA, et al. Among authors: boriack sjodin pa. Cell Chem Biol. 2018 Feb 15;25(2):128-134. doi: 10.1016/j.chembiol.2017.11.003. Epub 2017 Dec 7. Cell Chem Biol. 2018. PMID: 29233521 Free article. Review.
Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
Duncan KW, Rioux N, Boriack-Sjodin PA, Munchhof MJ, Reiter LA, Majer CR, Jin L, Johnston LD, Chan-Penebre E, Kuplast KG, Porter Scott M, Pollock RM, Waters NJ, Smith JJ, Moyer MP, Copeland RA, Chesworth R. Duncan KW, et al. Among authors: boriack sjodin pa. ACS Med Chem Lett. 2015 Dec 2;7(2):162-6. doi: 10.1021/acsmedchemlett.5b00380. eCollection 2016 Feb 11. ACS Med Chem Lett. 2015. PMID: 26985292 Free PMC article.
Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Mitchell LH, Boriack-Sjodin PA, Smith S, Thomenius M, Rioux N, Munchhof M, Mills JE, Klaus C, Totman J, Riera TV, Raimondi A, Jacques SL, West K, Foley M, Waters NJ, Kuntz KW, Wigle TJ, Scott MP, Copeland RA, Smith JJ, Chesworth R. Mitchell LH, et al. Among authors: boriack sjodin pa. ACS Med Chem Lett. 2015 Aug 27;7(2):134-8. doi: 10.1021/acsmedchemlett.5b00272. eCollection 2016 Feb 11. ACS Med Chem Lett. 2015. PMID: 26985287 Free PMC article.
48 results