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Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner.
Hoeft K, Schaefer GJL, Kim H, Schumacher D, Bleckwehl T, Long Q, Klinkhammer BM, Peisker F, Koch L, Nagai J, Halder M, Ziegler S, Liehn E, Kuppe C, Kranz J, Menzel S, Costa I, Wahida A, Boor P, Schneider RK, Hayat S, Kramann R. Hoeft K, et al. Among authors: boor p. Cell Rep. 2023 Feb 28;42(2):112131. doi: 10.1016/j.celrep.2023.112131. Epub 2023 Feb 18. Cell Rep. 2023. PMID: 36807143 Free PMC article.
2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function.
Moellmann J, Krueger K, Wong DWL, Klinkhammer BM, Buhl EM, Dehairs J, Swinnen JV, Noels H, Jankowski J, Lebherz C, Boor P, Marx N, Lehrke M. Moellmann J, et al. Among authors: boor p. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166825. doi: 10.1016/j.bbadis.2023.166825. Epub 2023 Aug 1. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37536502 Free article.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: boor p. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
The role of desmoglein-2 in kidney disease.
Xu T, Herkens L, Jia T, Klinkhammer BM, Kant S, Krusche CA, Buhl EM, Hayat S, Floege J, Strnad P, Kramann R, Djudjaj S, Boor P. Xu T, et al. Among authors: boor p. Kidney Int. 2024 May;105(5):1035-1048. doi: 10.1016/j.kint.2024.01.037. Epub 2024 Feb 21. Kidney Int. 2024. PMID: 38395410 Free article.
Deep learning applications for kidney histology analysis.
Pilva P, Bülow R, Boor P. Pilva P, et al. Among authors: boor p. Curr Opin Nephrol Hypertens. 2024 May 1;33(3):291-297. doi: 10.1097/MNH.0000000000000973. Epub 2024 Feb 19. Curr Opin Nephrol Hypertens. 2024. PMID: 38411024 Review.
539 results