Bonsignore R - Search Results

1

An Organometallic Gold(I) Bis-N-Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells.

Meier-Menches SM, Neuditschko B, Zappe K, Schaier M, Gerner MC, Schmetterer KG, Del Favero G, Bonsignore R, Cichna-Markl M, Koellensperger G, Casini A, Gerner C. Meier-Menches SM, et al. Among authors: bonsignore r. Chemistry. 2020 Dec 1;26(67):15528-15537. doi: 10.1002/chem.202003495. Epub 2020 Nov 3. Chemistry. 2020. PMID: 32902006 Free PMC article.

2

Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches.

Karaca Ö, Scalcon V, Meier-Menches SM, Bonsignore R, Brouwer JMJL, Tonolo F, Folda A, Rigobello MP, Kühn FE, Casini A. Karaca Ö, et al. Among authors: bonsignore r. Inorg Chem. 2017 Nov 20;56(22):14237-14250. doi: 10.1021/acs.inorgchem.7b02345. Epub 2017 Nov 2. Inorg Chem. 2017. PMID: 29095609

3

On the Mechanism of Gold/NHC Compounds Binding to DNA G-Quadruplexes: Combined Metadynamics and Biophysical Methods.

Wragg D, de Almeida A, Bonsignore R, Kühn FE, Leoni S, Casini A. Wragg D, et al. Among authors: bonsignore r. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14524-14528. doi: 10.1002/anie.201805727. Epub 2018 Jul 25. Angew Chem Int Ed Engl. 2018. PMID: 29972613

4

Cyclometalated Au^III Complexes for Cysteine Arylation in Zinc Finger Protein Domains: towards Controlled Reductive Elimination.

Wenzel MN, Bonsignore R, Thomas SR, Bourissou D, Barone G, Casini A. Wenzel MN, et al. Among authors: bonsignore r. Chemistry. 2019 Jun 7;25(32):7628-7634. doi: 10.1002/chem.201901535. Epub 2019 May 9. Chemistry. 2019. PMID: 30990916 Free PMC article.

5

Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold(I) complexes featuring N-heterocyclic carbene and alkynyl ligands.

Meier-Menches SM, Aikman B, Döllerer D, Klooster WT, Coles SJ, Santi N, Luk L, Casini A, Bonsignore R. Meier-Menches SM, et al. Among authors: bonsignore r. J Inorg Biochem. 2020 Jan;202:110844. doi: 10.1016/j.jinorgbio.2019.110844. Epub 2019 Sep 11. J Inorg Biochem. 2020. PMID: 31739113

6

Carbon-Phosphorus Coupling from C^N Cyclometalated Au^III Complexes.

Bonsignore R, Thomas SR, Klooster WT, Coles SJ, Jenkins RL, Bourissou D, Barone G, Casini A. Bonsignore R, et al. Chemistry. 2020 Apr 1;26(19):4226-4231. doi: 10.1002/chem.201905392. Epub 2020 Mar 6. Chemistry. 2020. PMID: 31994237 Free PMC article.

7

Exploring the Chemoselectivity towards Cysteine Arylation by Cyclometallated Au^III Compounds: New Mechanistic Insights.

Thomas SR, Bonsignore R, Sánchez Escudero J, Meier-Menches SM, Brown CM, Wolf MO, Barone G, Luk LYP, Casini A. Thomas SR, et al. Among authors: bonsignore r. Chembiochem. 2020 Nov 2;21(21):3071-3076. doi: 10.1002/cbic.202000262. Epub 2020 Jul 8. Chembiochem. 2020. PMID: 32511840 Free PMC article.

8

Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro.

Minori K, Rosa LB, Bonsignore R, Casini A, Miguel DC. Minori K, et al. Among authors: bonsignore r. ChemMedChem. 2020 Nov 18;15(22):2146-2150. doi: 10.1002/cmdc.202000536. Epub 2020 Sep 28. ChemMedChem. 2020. PMID: 32830445 Free PMC article.

9

An Organogold Compound as Potential Antimicrobial Agent against Drug-Resistant Bacteria: Initial Mechanistic Insights.

Chakraborty P, Oosterhuis D, Bonsignore R, Casini A, Olinga P, Scheffers DJ. Chakraborty P, et al. Among authors: bonsignore r. ChemMedChem. 2021 Oct 6;16(19):3060-3070. doi: 10.1002/cmdc.202100342. Epub 2021 Jul 23. ChemMedChem. 2021. PMID: 34181818 Free PMC article.

10

C-C Cross-Couplings from a Cyclometalated Au(III) C

^{\land}

N Complex: Mechanistic Insights and Synthetic Developments.

Bonsignore R, Thomas SR, Rigoulet M, Jandl C, Pöthig A, Bourissou D, Barone G, Casini A. Bonsignore R, et al. Chemistry. 2021 Oct 13;27(57):14322-14334. doi: 10.1002/chem.202102668. Epub 2021 Aug 28. Chemistry. 2021. PMID: 34310783 Free PMC article.

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