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Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial.
Yulug B, Altay O, Li X, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Yang H, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Hacimuftuoglu A, Yildirim S, Arif M, Shoaie S, Zhang C, Nielsen J, Turkez H, Borén J, Uhlén M, Mardinoglu A. Yulug B, et al. Among authors: bolat i. Transl Neurodegener. 2023 Jan 26;12(1):4. doi: 10.1186/s40035-023-00336-2. Transl Neurodegener. 2023. PMID: 36703196 Free PMC article. Clinical Trial.
Neuroprotective effects of dietary borax in the brain tissue of rainbow trout (Oncorhynchus mykiss) exposed to copper-induced toxicity.
Alak G, Ucar A, Yeltekin AÇ, Çomaklı S, Parlak V, Taş IH, Özkaraca M, Topal A, Kirman EM, Bolat İ, Atamanalp M, Türkez H. Alak G, et al. Among authors: bolat i. Fish Physiol Biochem. 2018 Oct;44(5):1409-1420. doi: 10.1007/s10695-018-0530-0. Epub 2018 Jun 29. Fish Physiol Biochem. 2018. PMID: 29959587 Clinical Trial.
Potential Neurotoxic Effects of Glioblastoma-Derived Exosomes in Primary Cultures of Cerebellar Neurons via Oxidant Stress and Glutathione Depletion.
Genc S, Pennisi M, Yeni Y, Yildirim S, Gattuso G, Altinoz MA, Taghizadehghalehjoughi A, Bolat I, Tsatsakis A, Hacımüftüoğlu A, Falzone L. Genc S, et al. Among authors: bolat i. Antioxidants (Basel). 2022 Jun 23;11(7):1225. doi: 10.3390/antiox11071225. Antioxidants (Basel). 2022. PMID: 35883716 Free PMC article.
Effects of boric acid and potassium metaborate on cytokine levels and redox stress parameters in a wound model infected with methicillin‑resistant Staphylococcus aureus.
Celebi D, Taghizadehghalehjoughi A, Baser S, Genc S, Yilmaz A, Yeni Y, Yesilyurt F, Yildirim S, Bolat I, Kordali S, Yilmaz F, Hacimuftuoglu A, Celebi O, Margina D, Nitulescu GM, Spandidos DA, Tsatsakis A. Celebi D, et al. Among authors: bolat i. Mol Med Rep. 2022 Sep;26(3):294. doi: 10.3892/mmr.2022.12809. Epub 2022 Aug 3. Mol Med Rep. 2022. PMID: 35920188 Free PMC article.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning.
Zhang C, Shi M, Kim W, Arif M, Klevstig M, Li X, Yang H, Bayram C, Bolat I, Tozlu ÖÖ, Hacımuftuoglu A, Yıldırım S, Sebhaoui J, Iqbal S, Wei Y, Shi X, Nielsen J, Turkez H, Uhlen M, Boren J, Mardinoglu A. Zhang C, et al. Among authors: bolat i. EBioMedicine. 2022 Sep;83:104214. doi: 10.1016/j.ebiom.2022.104214. Epub 2022 Aug 18. EBioMedicine. 2022. PMID: 35988463 Free PMC article.
Artichoke (Cynara Scolymus) Methanolic Leaf Extract Alleviates Diethylnitrosamine-Induced Toxicity in BALB/c Mouse Brain: Involvement of Oxidative Stress and Apoptotically Related Klotho/PPARγ Signaling.
Cicek B, Genc S, Yeni Y, Kuzucu M, Cetin A, Yildirim S, Bolat I, Kantarci M, Hacimuftuoglu A, Lazopoulos G, Tsatsakis A, Tsarouhas K, Taghizadehghalehjoughi A. Cicek B, et al. Among authors: bolat i. J Pers Med. 2022 Dec 4;12(12):2012. doi: 10.3390/jpm12122012. J Pers Med. 2022. PMID: 36556233 Free PMC article.
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases.
Turkez H, Altay O, Yildirim S, Li X, Yang H, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Arif M, Yulug B, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Hacimuftuoglu A, Shoaie S, Zhang C, Nielsen J, Borén J, Uhlén M, Mardinoglu A. Turkez H, et al. Among authors: bolat i. Life Sci. 2023 Feb 1;314:121325. doi: 10.1016/j.lfs.2022.121325. Epub 2022 Dec 26. Life Sci. 2023. PMID: 36581096 Free article.
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Gao C, Akladios F, Kim W, Yang H, Bayram C, Bolat I, Kiliclioglu M, Yuksel N, Tozlu OO, Zhang C, Sebhaoui J, Iqbal S, Shoaie S, Hacimuftuoglu A, Yildirim S, Turkez H, Uhlen M, Boren J, Mardinoglu A, Grøtli M. Battisti UM, et al. Among authors: bolat i. Nutrients. 2023 Jan 22;15(3):577. doi: 10.3390/nu15030577. Nutrients. 2023. PMID: 36771285 Free PMC article.
84 results