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Sodium acetate increases the productivity of HEK293 cells expressing the ECD-Her1 protein in batch cultures: experimental results and metabolic flux analysis.
Front Bioeng Biotechnol. 2024 Apr 10;12:1335898. doi: 10.3389/fbioe.2024.1335898. eCollection 2024.
Front Bioeng Biotechnol. 2024.
PMID: 38659646
Free PMC article.
HEK293 producing the extracellular domain HER1: Full datasets of continuous fermentation process and metabolites analysis.
Calzadilla L, Hernández E, Dustet J, Fernandez-de-Cossio-Diaz J, León K, Pietzke M, Vazquez A, Mulet R, Boggiano T.
Calzadilla L, et al. Among authors: boggiano t.
Data Brief. 2023 Sep 21;50:109604. doi: 10.1016/j.dib.2023.109604. eCollection 2023 Oct.
Data Brief. 2023.
PMID: 37808545
Free PMC article.
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A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles.
Santana-Mederos D, Perez-Nicado R, Climent Y, Rodriguez L, Ramirez BS, Perez-Rodriguez S, Rodriguez M, Labrada C, Hernandez T, Diaz M, Orosa I, Ramirez U, Oliva R, Garrido R, Cardoso F, Landys M, Martinez R, Gonzalez H, Hernandez T, Ochoa-Azze R, Perez JL, Enriquez J, Gonzalez N, Infante Y, Espinosa LA, Ramos Y, González LJ, Valenzuela C, Casadesus AV, Fernandez B, Rojas G, Pérez-Massón B, Tundidor Y, Bermudez E, Plasencia CA, Boggiano T, Ojito E, Chiodo F, Fernandez S, Paquet F, Fang C, Chen GW, Rivera DG, Valdes-Balbin Y, Garcia-Rivera D, Verez Bencomo V.
Santana-Mederos D, et al. Among authors: boggiano t.
RSC Chem Biol. 2021 Dec 8;3(2):242-249. doi: 10.1039/d1cb00200g. eCollection 2022 Feb 9.
RSC Chem Biol. 2021.
PMID: 35360883
Free PMC article.
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In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a single ESI-MS spectrum.
Espinosa LA, Ramos Y, Andújar I, Torres EO, Cabrera G, Martín A, Roche D, Chinea G, Becquet M, González I, Canaán-Haden C, Nelson E, Rojas G, Pérez-Massón B, Pérez-Martínez D, Boggiano T, Palacio J, Lozada Chang SL, Hernández L, de la Luz Hernández KR, Markku S, Vitikainen M, Valdés-Balbín Y, Santana-Medero D, Rivera DG, Vérez-Bencomo V, Emalfarb M, Tchelet R, Guillén G, Limonta M, Pimentel E, Ayala M, Besada V, González LJ.
Espinosa LA, et al. Among authors: boggiano t.
Anal Bioanal Chem. 2021 Dec;413(30):7559-7585. doi: 10.1007/s00216-021-03721-w. Epub 2021 Nov 5.
Anal Bioanal Chem. 2021.
PMID: 34739558
Free PMC article.
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SARS-CoV-2 RBD-Tetanus Toxoid Conjugate Vaccine Induces a Strong Neutralizing Immunity in Preclinical Studies.
Valdes-Balbin Y, Santana-Mederos D, Quintero L, Fernández S, Rodriguez L, Sanchez Ramirez B, Perez-Nicado R, Acosta C, Méndez Y, Ricardo MG, Hernandez T, Bergado G, Pi F, Valdes A, Carmenate T, Ramirez U, Oliva R, Soubal JP, Garrido R, Cardoso F, Landys M, Gonzalez H, Farinas M, Enriquez J, Noa E, Suarez A, Fang C, Espinosa LA, Ramos Y, González LJ, Climent Y, Rojas G, Relova-Hernández E, Cabrera Infante Y, Losada SL, Boggiano T, Ojito E, León K, Chiodo F, Paquet F, Chen GW, Rivera DG, Garcia-Rivera D, Verez Bencomo V.
Valdes-Balbin Y, et al. Among authors: boggiano t.
ACS Chem Biol. 2021 Jul 16;16(7):1223-1233. doi: 10.1021/acschembio.1c00272. Epub 2021 Jul 4.
ACS Chem Biol. 2021.
PMID: 34219448
Free article.
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In-silico media optimization for continuous cultures using genome scale metabolic networks: The case of CHO-K1.
Pérez-Fernández BA, Fernandez-de-Cossio-Diaz J, Boggiano T, León K, Mulet R.
Pérez-Fernández BA, et al. Among authors: boggiano t.
Biotechnol Bioeng. 2021 May;118(5):1884-1897. doi: 10.1002/bit.27704. Epub 2021 Mar 1.
Biotechnol Bioeng. 2021.
PMID: 33554345
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