Blenis J - Search Results

1

An atlas of substrate specificities for the human serine/threonine kinome.

Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, van Vlimmeren AE, Andrée-Busch N, Käufer NF, Dorovkov MV, Ryazanov AG, Takagi Y, Kastenhuber ER, Goncalves MD, Hopkins BD, Elemento O, Taatjes DJ, Maucuer A, Yamashita A, Degterev A, Uduman M, Lu J, Landry SD, Zhang B, Cossentino I, Linding R, Blenis J, Hornbeck PV, Turk BE, Yaffe MB, Cantley LC. Johnson JL, et al. Among authors: blenis j. Nature. 2023 Jan;613(7945):759-766. doi: 10.1038/s41586-022-05575-3. Epub 2023 Jan 11. Nature. 2023. PMID: 36631611 Free PMC article.

2

Coordinate regulation of pp90rsk and a distinct protein-serine/threonine kinase activity that phosphorylates recombinant pp90rsk in vitro.

Chung J, Chen RH, Blenis J. Chung J, et al. Among authors: blenis j. Mol Cell Biol. 1991 Apr;11(4):1868-74. doi: 10.1128/mcb.11.4.1868-1874.1991. Mol Cell Biol. 1991. PMID: 1826043 Free PMC article.

3

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase.

Chung J, Grammer TC, Lemon KP, Kazlauskas A, Blenis J. Chung J, et al. Among authors: blenis j. Nature. 1994 Jul 7;370(6484):71-5. doi: 10.1038/370071a0. Nature. 1994. PMID: 8015612

4

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

Songyang Z, Lu KP, Kwon YT, Tsai LH, Filhol O, Cochet C, Brickey DA, Soderling TR, Bartleson C, Graves DJ, DeMaggio AJ, Hoekstra MF, Blenis J, Hunter T, Cantley LC. Songyang Z, et al. Among authors: blenis j. Mol Cell Biol. 1996 Nov;16(11):6486-93. doi: 10.1128/MCB.16.11.6486. Mol Cell Biol. 1996. PMID: 8887677 Free PMC article.

5

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway.

Manning BD, Tee AR, Logsdon MN, Blenis J, Cantley LC. Manning BD, et al. Among authors: blenis j. Mol Cell. 2002 Jul;10(1):151-62. doi: 10.1016/s1097-2765(02)00568-3. Mol Cell. 2002. PMID: 12150915 Free article.

6

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.

Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J. Tee AR, et al. Among authors: blenis j. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13571-6. doi: 10.1073/pnas.202476899. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271141 Free PMC article.

7

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.

Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. Tee AR, et al. Among authors: blenis j. Curr Biol. 2003 Aug 5;13(15):1259-68. doi: 10.1016/s0960-9822(03)00506-2. Curr Biol. 2003. PMID: 12906785 Free article.

8

The RSK family of kinases: emerging roles in cellular signalling.

Anjum R, Blenis J. Anjum R, et al. Among authors: blenis j. Nat Rev Mol Cell Biol. 2008 Oct;9(10):747-58. doi: 10.1038/nrm2509. Nat Rev Mol Cell Biol. 2008. PMID: 18813292 Review.

9

Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply.

Choo AY, Kim SG, Vander Heiden MG, Mahoney SJ, Vu H, Yoon SO, Cantley LC, Blenis J. Choo AY, et al. Among authors: blenis j. Mol Cell. 2010 May 28;38(4):487-99. doi: 10.1016/j.molcel.2010.05.007. Mol Cell. 2010. PMID: 20513425 Free PMC article.

10

Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.

Yu Y, Yoon SO, Poulogiannis G, Yang Q, Ma XM, Villén J, Kubica N, Hoffman GR, Cantley LC, Gygi SP, Blenis J. Yu Y, et al. Among authors: blenis j. Science. 2011 Jun 10;332(6035):1322-6. doi: 10.1126/science.1199484. Science. 2011. PMID: 21659605 Free PMC article.

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