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Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
J Med Chem. 2022 Oct 27;65(20):13879-13891. doi: 10.1021/acs.jmedchem.2c01142. Epub 2022 Oct 6.
J Med Chem. 2022.
PMID: 36200480
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Zatreanu D, Robinson HMR, Alkhatib O, Boursier M, Finch H, Geo L, Grande D, Grinkevich V, Heald RA, Langdon S, Majithiya J, McWhirter C, Martin NMB, Moore S, Neves J, Rajendra E, Ranzani M, Schaedler T, Stockley M, Wiggins K, Brough R, Sridhar S, Gulati A, Shao N, Badder LM, Novo D, Knight EG, Marlow R, Haider S, Callen E, Hewitt G, Schimmel J, Prevo R, Alli C, Ferdinand A, Bell C, Blencowe P, Bot C, Calder M, Charles M, Curry J, Ekwuru T, Ewings K, Krajewski W, MacDonald E, McCarron H, Pang L, Pedder C, Rigoreau L, Swarbrick M, Wheatley E, Willis S, Wong AC, Nussenzweig A, Tijsterman M, Tutt A, Boulton SJ, Higgins GS, Pettitt SJ, Smith GCM, Lord CJ.
Zatreanu D, et al. Among authors: blencowe p.
Nat Commun. 2021 Jun 17;12(1):3636. doi: 10.1038/s41467-021-23463-8.
Nat Commun. 2021.
PMID: 34140467
Free PMC article.
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Correction to "Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta".
Stockley ML, Benedetti G, Blencowe P, Boulton SJ, Boyd SM, Calder M, Charles MD, Edwardes LV, Ekwuru T, Ferdinand A, Finch H, Galbiati A, Geo L, Grande D, Grinkevich V, Higgins GS, Holliday ND, Krajewski WW, MacDonald E, Majithiya JB, McCarron H, McWhirter CL, Patel V, Pedder C, Rajendra E, Ranzani M, Rigoreau LJM, Robinson HMR, Schaedler T, Sirina J, Smith GCM, Swarbrick ME, Turnbull AP, Willis S, Zemla A, Heald RA.
Stockley ML, et al. Among authors: blencowe p.
J Med Chem. 2023 Feb 23. doi: 10.1021/acs.jmedchem.3c00204. Online ahead of print.
J Med Chem. 2023.
PMID: 36815444
No abstract available.
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Selective Hydroxylation of C(sp3 )-H Bonds in Steroids.
Abas H, Blencowe P, Brookfield JL, Harwood LA.
Abas H, et al. Among authors: blencowe p.
Chemistry. 2023 Aug 4;29(44):e202301066. doi: 10.1002/chem.202301066. Epub 2023 Jul 12.
Chemistry. 2023.
PMID: 37235530
Review.
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Evaluating the efficacy of a digital App to enhance patient-centred nursing handover: A simulation study.
Yuen EYN, Street M, Abdelrazek M, Blencowe P, Etienne G, Liskaser R, Choudhary N, Considine J.
Yuen EYN, et al. Among authors: blencowe p.
J Clin Nurs. 2023 Oct;32(19-20):7626-7637. doi: 10.1111/jocn.16782. Epub 2023 Jul 13.
J Clin Nurs. 2023.
PMID: 37439324
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Access to family planning clinics--a local experience.
Reed B, Francis C, Blencowe P, Lamb V.
Reed B, et al. Among authors: blencowe p.
Eur J Contracept Reprod Health Care. 1999 Mar;4(1):49-53. doi: 10.3109/13625189909043481.
Eur J Contracept Reprod Health Care. 1999.
PMID: 10367197
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