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Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication.
Stegmann KM, Dickmanns A, Heinen N, Blaurock C, Karrasch T, Breithaupt A, Klopfleisch R, Uhlig N, Eberlein V, Issmail L, Herrmann ST, Schreieck A, Peelen E, Kohlhof H, Sadeghi B, Riek A, Speakman JR, Groß U, Görlich D, Vitt D, Müller T, Grunwald T, Pfaender S, Balkema-Buschmann A, Dobbelstein M. Stegmann KM, et al. Among authors: blaurock c. iScience. 2022 May 20;25(5):104293. doi: 10.1016/j.isci.2022.104293. Epub 2022 Apr 25. iScience. 2022. PMID: 35492218 Free PMC article.
Genetic incompatibilities and reduced transmission in chickens may limit the evolution of reassortants between H9N2 and panzootic H5N8 clade 2.3.4.4 avian influenza virus showing high virulence for mammals.
Mostafa A, Blaurock C, Scheibner D, Müller C, Blohm U, Schäfer A, Gischke M, Salaheldin AH, Nooh HZ, Ali MA, Breithaupt A, Mettenleiter TC, Pleschka S, Abdelwhab EM. Mostafa A, et al. Among authors: blaurock c. Virus Evol. 2020 Oct 15;6(2):veaa077. doi: 10.1093/ve/veaa077. eCollection 2020 Jul. Virus Evol. 2020. PMID: 33343923 Free PMC article.
The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo.
Gischke M, Bagato O, Breithaupt A, Scheibner D, Blaurock C, Vallbracht M, Karger A, Crossley B, Veits J, Böttcher-Friebertshäuser E, Mettenleiter TC, Abdelwhab EM. Gischke M, et al. Among authors: blaurock c. Virulence. 2021 Dec;12(1):666-678. doi: 10.1080/21505594.2021.1881344. Virulence. 2021. PMID: 33538209 Free PMC article.
13 results