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SIRT1 promotes differentiation of normal human keratinocytes.
Blander G, Bhimavarapu A, Mammone T, Maes D, Elliston K, Reich C, Matsui MS, Guarente L, Loureiro JJ. Blander G, et al. J Invest Dermatol. 2009 Jan;129(1):41-9. doi: 10.1038/jid.2008.179. Epub 2008 Jun 19. J Invest Dermatol. 2009. PMID: 18563176 Free PMC article.
The Sir2 family of protein deacetylases.
Blander G, Guarente L. Blander G, et al. Annu Rev Biochem. 2004;73:417-35. doi: 10.1146/annurev.biochem.73.011303.073651. Annu Rev Biochem. 2004. PMID: 15189148 Review.
SIRT1 shows no substrate specificity in vitro.
Blander G, Olejnik J, Krzymanska-Olejnik E, McDonagh T, Haigis M, Yaffe MB, Guarente L. Blander G, et al. J Biol Chem. 2005 Mar 18;280(11):9780-5. doi: 10.1074/jbc.M414080200. Epub 2005 Jan 6. J Biol Chem. 2005. PMID: 15640142 Free article.
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.
Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA. Firestein R, et al. Among authors: blander g. PLoS One. 2008 Apr 16;3(4):e2020. doi: 10.1371/journal.pone.0002020. PLoS One. 2008. PMID: 18414679 Free PMC article.
Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.
Deehan R, Maerz-Weiss P, Catlett NL, Steiner G, Wong B, Wright MB, Blander G, Elliston KO, Ladd W, Bobadilla M, Mizrahi J, Haefliger C, Edgar A. Deehan R, et al. Among authors: blander g. PLoS One. 2012;7(4):e35012. doi: 10.1371/journal.pone.0035012. Epub 2012 Apr 13. PLoS One. 2012. PMID: 22514701 Free PMC article.
17 results