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Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance.
Safi H, Gopal P, Lingaraju S, Ma S, Levine C, Dartois V, Yee M, Li L, Blanc L, Ho Liang HP, Husain S, Hoque M, Soteropoulos P, Rustad T, Sherman DR, Dick T, Alland D. Safi H, et al. Among authors: blanc l. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19665-19674. doi: 10.1073/pnas.1907631116. Epub 2019 Sep 5. Proc Natl Acad Sci U S A. 2019. PMID: 31488707 Free PMC article.
Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum.
Sarathy JP, Via LE, Weiner D, Blanc L, Boshoff H, Eugenin EA, Barry CE 3rd, Dartois VA. Sarathy JP, et al. Among authors: blanc l. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e02266-17. doi: 10.1128/AAC.02266-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29203492 Free PMC article.
Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.
Sarathy J, Blanc L, Alvarez-Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Zimmerman M, Kaya F, Ho Liang HP, Prideaux B, Dietzold J, Salgame P, Savic RM, Linderman J, Kirschner D, Pienaar E, Dartois V. Sarathy J, et al. Among authors: blanc l. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02516-18. doi: 10.1128/AAC.02516-18. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30803965 Free PMC article.
Impact of immunopathology on the antituberculous activity of pyrazinamide.
Blanc L, Sarathy JP, Alvarez Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Sacchettini J, Savic RM, Gengenbacher M, Podell BK, Prideaux B, Ioerger T, Dick T, Dartois V. Blanc L, et al. J Exp Med. 2018 Aug 6;215(8):1975-1986. doi: 10.1084/jem.20180518. Epub 2018 Jul 17. J Exp Med. 2018. PMID: 30018074 Free PMC article.
Ethambutol Partitioning in Tuberculous Pulmonary Lesions Explains Its Clinical Efficacy.
Zimmerman M, Lestner J, Prideaux B, O'Brien P, Dias-Freedman I, Chen C, Dietzold J, Daudelin I, Kaya F, Blanc L, Chen PY, Park S, Salgame P, Sarathy J, Dartois V. Zimmerman M, et al. Among authors: blanc l. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00924-17. doi: 10.1128/AAC.00924-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28696241 Free PMC article.
197 results