Blacklow SC - Search Results

1

Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling.

Gonzalez-Perez D, Das S, Antfolk D, Ahsan HS, Medina E, Dundes CE, Jokhai RT, Egan ED, Blacklow SC, Loh KM, Rodriguez PC, Luca VC. Gonzalez-Perez D, et al. Among authors: blacklow sc. Nat Chem Biol. 2023 Jan;19(1):9-17. doi: 10.1038/s41589-022-01113-4. Epub 2022 Sep 1. Nat Chem Biol. 2023. PMID: 36050494 Free PMC article.

2

Notch signaling as a therapeutic target.

Nam Y, Aster JC, Blacklow SC. Nam Y, et al. Among authors: blacklow sc. Curr Opin Chem Biol. 2002 Aug;6(4):501-9. doi: 10.1016/s1367-5931(02)00346-0. Curr Opin Chem Biol. 2002. PMID: 12133727 Review.

3

Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations.

McMillan BJ, Zimmerman B, Egan ED, Lofgren M, Xu X, Hesser A, Blacklow SC. McMillan BJ, et al. Among authors: blacklow sc. Glycobiology. 2017 Aug 1;27(8):777-786. doi: 10.1093/glycob/cwx020. Glycobiology. 2017. PMID: 28334865 Free PMC article.

4

Signal Transduction: Notch catches a Jagged edge.

Blacklow SC. Blacklow SC. Nat Chem Biol. 2017 May 17;13(6):570-571. doi: 10.1038/nchembio.2379. Nat Chem Biol. 2017. PMID: 28514425 Free PMC article.

5

MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation.

Rogers JM, Guo B, Egan ED, Aster JC, Adelman K, Blacklow SC. Rogers JM, et al. Among authors: blacklow sc. Mol Cell Biol. 2020 May 14;40(11):e00014-20. doi: 10.1128/MCB.00014-20. Print 2020 May 14. Mol Cell Biol. 2020. PMID: 32179552 Free PMC article.

6

Functional Comparison between Endogenous and Synthetic Notch Systems.

Khamaisi B, Luca VC, Blacklow SC, Sprinzak D. Khamaisi B, et al. Among authors: blacklow sc. ACS Synth Biol. 2022 Oct 21;11(10):3343-3353. doi: 10.1021/acssynbio.2c00247. Epub 2022 Sep 15. ACS Synth Biol. 2022. PMID: 36107643 Free PMC article.

7

Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling.

Jones DTD, Dates AN, Rawson SD, Burruss MM, Lipper CH, Blacklow SC. Jones DTD, et al. Among authors: blacklow sc. Nat Commun. 2023 Apr 29;14(1):2490. doi: 10.1038/s41467-023-38083-7. Nat Commun. 2023. PMID: 37120430 Free PMC article.

8

Structural basis for membrane-proximal proteolysis of substrates by ADAM10.

Lipper CH, Egan ED, Gabriel KH, Blacklow SC. Lipper CH, et al. Among authors: blacklow sc. Cell. 2023 Aug 17;186(17):3632-3641.e10. doi: 10.1016/j.cell.2023.06.026. Epub 2023 Jul 28. Cell. 2023. PMID: 37516108

9

A spatiotemporal Notch interaction map from plasma membrane to nucleus.

Martin AP, Bradshaw GA, Eisert RJ, Egan ED, Tveriakhina L, Rogers JM, Dates AN, Scanavachi G, Aster JC, Kirchhausen T, Kalocsay M, Blacklow SC. Martin AP, et al. Among authors: blacklow sc. Sci Signal. 2023 Aug;16(796):eadg6474. doi: 10.1126/scisignal.adg6474. Epub 2023 Aug 1. Sci Signal. 2023. PMID: 37527352 Free PMC article.

10

Temporal Dynamics and Stoichiometry in Notch Signaling - from Notch Synaptic Complex Formation to NICD Nuclear Entry.

Tveriakhina L, Scanavachi G, Egan ED, Correia RBDC, Martin AP, Rogers JM, Yodh JS, Aster JC, Kirchhausen T, Blacklow SC. Tveriakhina L, et al. Among authors: blacklow sc. bioRxiv [Preprint]. 2023 Sep 28:2023.09.27.559780. doi: 10.1101/2023.09.27.559780. bioRxiv. 2023. PMID: 37808809 Free PMC article. Updated. Preprint.

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