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The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling.
Ackermann M, Kamp JC, Werlein C, Walsh CL, Stark H, Prade V, Surabattula R, Wagner WL, Disney C, Bodey AJ, Illig T, Leeming DJ, Karsdal MA, Tzankov A, Boor P, Kühnel MP, Länger FP, Verleden SE, Kvasnicka HM, Kreipe HH, Haverich A, Black SM, Walch A, Tafforeau P, Lee PD, Hoeper MM, Welte T, Seeliger B, David S, Schuppan D, Mentzer SJ, Jonigk DD. Ackermann M, et al. Among authors: black sm. EBioMedicine. 2022 Nov;85:104296. doi: 10.1016/j.ebiom.2022.104296. Epub 2022 Oct 4. EBioMedicine. 2022. PMID: 36206625 Free PMC article.
NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling.
Barman SA, Chen F, Su Y, Dimitropoulou C, Wang Y, Catravas JD, Han W, Orfi L, Szantai-Kis C, Keri G, Szabadkai I, Barabutis N, Rafikova O, Rafikov R, Black SM, Jonigk D, Giannis A, Asmis R, Stepp DW, Ramesh G, Fulton DJ. Barman SA, et al. Among authors: black sm. Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1704-15. doi: 10.1161/ATVBAHA.114.303848. Epub 2014 Jun 19. Arterioscler Thromb Vasc Biol. 2014. PMID: 24947524 Free PMC article.
Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Tang H, Babicheva A, McDermott KM, Gu Y, Ayon RJ, Song S, Wang Z, Gupta A, Zhou T, Sun X, Dash S, Wang Z, Balistrieri A, Zheng Q, Cordery AG, Desai AA, Rischard F, Khalpey Z, Wang J, Black SM, Garcia JGN, Makino A, Yuan JX. Tang H, et al. Among authors: black sm. Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L256-L275. doi: 10.1152/ajplung.00096.2017. Epub 2017 Oct 26. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29074488 Free PMC article.
Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase.
Sun X, Kumar S, Sharma S, Aggarwal S, Lu Q, Gross C, Rafikova O, Lee SG, Dasarathy S, Hou Y, Meadows ML, Han W, Su Y, Fineman JR, Black SM. Sun X, et al. Among authors: black sm. Am J Respir Cell Mol Biol. 2014 Jun;50(6):1084-95. doi: 10.1165/rcmb.2013-0187OC. Am J Respir Cell Mol Biol. 2014. PMID: 24392990 Free PMC article.
404 results