Bittner MA - Search Results

1

Roles for the SNAP25 linker domain in the fusion pore and a dynamic plasma membrane SNARE "acceptor" complex.

Holz RW, Bittner MA. Holz RW, et al. Among authors: bittner ma. J Gen Physiol. 2020 Sep 7;152(9):e202012619. doi: 10.1085/jgp.202012619. J Gen Physiol. 2020. PMID: 32722752 Free PMC article.

2

Identification of β-synuclein on secretory granules in chromaffin cells and the effects of α- and β-synuclein on post-fusion BDNF discharge and fusion pore expansion.

Abbineni PS, Bohannon KP, Bittner MA, Axelrod D, Holz RW. Abbineni PS, et al. Among authors: bittner ma. Neurosci Lett. 2019 Apr 23;699:134-139. doi: 10.1016/j.neulet.2019.01.056. Epub 2019 Jan 31. Neurosci Lett. 2019. PMID: 30711526 Free PMC article.

3

Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion.

Abbineni PS, Bittner MA, Axelrod D, Holz RW. Abbineni PS, et al. Among authors: bittner ma. J Gen Physiol. 2019 Feb 4;151(2):118-130. doi: 10.1085/jgp.201812182. Epub 2018 Nov 30. J Gen Physiol. 2019. PMID: 30504267 Free PMC article.

4

Slow fusion pore expansion creates a unique reaction chamber for co-packaged cargo.

Bohannon KP, Bittner MA, Lawrence DA, Axelrod D, Holz RW. Bohannon KP, et al. Among authors: bittner ma. J Gen Physiol. 2017 Oct 2;149(10):921-934. doi: 10.1085/jgp.201711842. Epub 2017 Sep 7. J Gen Physiol. 2017. PMID: 28882880 Free PMC article.

5

Lumenal protein within secretory granules affects fusion pore expansion.

Weiss AN, Anantharam A, Bittner MA, Axelrod D, Holz RW. Weiss AN, et al. Among authors: bittner ma. Biophys J. 2014 Jul 1;107(1):26-33. doi: 10.1016/j.bpj.2014.04.064. Biophys J. 2014. PMID: 24988338 Free PMC article.

6

Protein mobility within secretory granules.

Weiss AN, Bittner MA, Holz RW, Axelrod D. Weiss AN, et al. Among authors: bittner ma. Biophys J. 2014 Jul 1;107(1):16-25. doi: 10.1016/j.bpj.2014.04.063. Biophys J. 2014. PMID: 24988337 Free PMC article.

7

Discovery of novel insulin-like growth factor-1 receptor inhibitors with unique time-dependent binding kinetics.

Jin M, Petronella BA, Cooke A, Kadalbajoo M, Siu KW, Kleinberg A, May EW, Gokhale PC, Schulz R, Kahler J, Bittner MA, Foreman K, Pachter JA, Wild R, Epstein D, Mulvihill MJ. Jin M, et al. Among authors: bittner ma. ACS Med Chem Lett. 2013 May 23;4(7):627-31. doi: 10.1021/ml400160a. eCollection 2013 Jul 11. ACS Med Chem Lett. 2013. PMID: 24900721 Free PMC article.

8

A nibbling mechanism for clathrin-mediated retrieval of secretory granule membrane after exocytosis.

Bittner MA, Aikman RL, Holz RW. Bittner MA, et al. J Biol Chem. 2013 Mar 29;288(13):9177-88. doi: 10.1074/jbc.M113.450361. Epub 2013 Feb 5. J Biol Chem. 2013. PMID: 23386611 Free PMC article.

9

Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.

Jin M, Wang J, Kleinberg A, Kadalbajoo M, Siu KW, Cooke A, Bittner MA, Yao Y, Thelemann A, Ji Q, Bhagwat S, Mulvihill KM, Rechka JA, Pachter JA, Crew AP, Epstein D, Mulvihill MJ. Jin M, et al. Among authors: bittner ma. Bioorg Med Chem Lett. 2013 Feb 15;23(4):979-84. doi: 10.1016/j.bmcl.2012.12.042. Epub 2012 Dec 21. Bioorg Med Chem Lett. 2013. PMID: 23317569

10

A new role for the dynamin GTPase in the regulation of fusion pore expansion.

Anantharam A, Bittner MA, Aikman RL, Stuenkel EL, Schmid SL, Axelrod D, Holz RW. Anantharam A, et al. Among authors: bittner ma. Mol Biol Cell. 2011 Jun 1;22(11):1907-18. doi: 10.1091/mbc.E11-02-0101. Epub 2011 Apr 1. Mol Biol Cell. 2011. PMID: 21460182 Free PMC article.

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