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Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis.
Li M, Yang L, Chan AKN, Pokharel SP, Liu Q, Mattson N, Xu X, Chang WH, Miyashita K, Singh P, Zhang L, Li M, Wu J, Wang J, Chen B, Chan LN, Lee J, Zhang XH, Rosen ST, Müschen M, Qi J, Chen J, Hiom K, Bishop AJR, Chen CW. Li M, et al. Among authors: bishop ajr. Adv Sci (Weinh). 2023 Jun;10(17):e2206584. doi: 10.1002/advs.202206584. Epub 2023 Apr 19. Adv Sci (Weinh). 2023. PMID: 37075745 Free PMC article.
EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.
Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR. Gorthi A, et al. Among authors: bishop ajr. Nature. 2018 Mar 15;555(7696):387-391. doi: 10.1038/nature25748. Epub 2018 Mar 7. Nature. 2018. PMID: 29513652 Free PMC article.
RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma.
Randolph ME, Afifi M, Gorthi A, Weil R, Wilky BA, Weinreb J, Ciero P, Ter Hoeve N, van Diest PJ, Raman V, Bishop AJR, Loeb DM. Randolph ME, et al. Among authors: bishop ajr. bioRxiv [Preprint]. 2023 Jun 10:2023.06.10.544474. doi: 10.1101/2023.06.10.544474. bioRxiv. 2023. PMID: 37333164 Free PMC article. Updated. Preprint.
Approaches for Mapping and Analysis of R-loops.
Mukhopadhyay P, Miller H, Stoja A, Bishop AJR. Mukhopadhyay P, et al. Among authors: bishop ajr. Curr Protoc. 2024 Apr;4(4):e1037. doi: 10.1002/cpz1.1037. Curr Protoc. 2024. PMID: 38666626 Review.
RNA helicase DDX3 regulates RAD51 localization and DNA damage repair in Ewing sarcoma.
Randolph ME, Afifi M, Gorthi A, Weil R, Wilky BA, Weinreb J, Ciero P, Hoeve NT, van Diest PJ, Raman V, Bishop AJR, Loeb DM. Randolph ME, et al. Among authors: bishop ajr. iScience. 2024 Jan 16;27(2):108925. doi: 10.1016/j.isci.2024.108925. eCollection 2024 Feb 16. iScience. 2024. PMID: 38323009 Free PMC article.
Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children's Oncology Group Phase 1 Consortium study (ADVL1411).
Schafer ES, Rau RE, Berg SL, Liu X, Minard CG, Bishop AJR, Romero JC, Hicks MJ, Nelson MD Jr, Voss S, Reid JM, Fox E, Weigel BJ, Blaney SM. Schafer ES, et al. Among authors: bishop ajr. Pediatr Blood Cancer. 2020 Feb;67(2):e28073. doi: 10.1002/pbc.28073. Epub 2019 Nov 14. Pediatr Blood Cancer. 2020. PMID: 31724813 Free PMC article. Clinical Trial.
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.
Jaiswal AS, Dutta A, Srinivasan G, Yuan Y, Zhou D, Shaheen M, Sadideen DT, Kirby A, Williamson EA, Gupta YK, Olsen SK, Xu M, Loranc E, Mukhopadhyay P, Pertsemlidis A, Bishop AJR, Sung P, Nickoloff JA, Hromas R. Jaiswal AS, et al. Among authors: bishop ajr. Nucleic Acids Res. 2023 Dec 11;51(22):12224-12241. doi: 10.1093/nar/gkad952. Nucleic Acids Res. 2023. PMID: 37953292 Free PMC article.
67 results