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Page 1
Novel S1P1 receptor agonists--part 1: From pyrazoles to thiophenes.
Bolli MH, Müller C, Mathys B, Abele S, Birker M, Bravo R, Bur D, Hess P, Kohl C, Lehmann D, Nayler O, Rey M, Meyer S, Scherz M, Schmidt G, Steiner B, Treiber A, Velker J, Weller T. Bolli MH, et al. Among authors: birker m. J Med Chem. 2013 Dec 12;56(23):9737-55. doi: 10.1021/jm4014373. Epub 2013 Nov 22. J Med Chem. 2013. PMID: 24266709
Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.
Bolli MH, Abele S, Birker M, Bravo R, Bur D, de Kanter R, Kohl C, Grimont J, Hess P, Lescop C, Mathys B, Müller C, Nayler O, Rey M, Scherz M, Schmidt G, Seifert J, Steiner B, Velker J, Weller T. Bolli MH, et al. Among authors: birker m. J Med Chem. 2014 Jan 9;57(1):110-30. doi: 10.1021/jm4014696. Epub 2013 Dec 24. J Med Chem. 2014. PMID: 24367923
Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.
Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B. Bolli MH, et al. Among authors: birker m. Eur J Med Chem. 2016 Jun 10;115:326-41. doi: 10.1016/j.ejmech.2016.03.020. Epub 2016 Mar 12. Eur J Med Chem. 2016. PMID: 27027817
Discovery of a Novel Orally Active, Selective LPA Receptor Type 1 Antagonist, 4-(4-(2-Isopropylphenyl)-4-((2-methoxy-4-methylphenyl)carbamoyl)piperidin-1-yl)-4-oxobutanoic Acid, with a Distinct Molecular Scaffold.
Lescop C, Brotschi C, Williams JT, Sager CP, Birker M, Morrison K, Froidevaux S, Delahaye S, Nayler O, Bolli MH. Lescop C, et al. Among authors: birker m. J Med Chem. 2024 Feb 22;67(4):2379-2396. doi: 10.1021/acs.jmedchem.3c01826. Epub 2024 Feb 13. J Med Chem. 2024. PMID: 38349223