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Impaired immune surveillance accelerates accumulation of senescent cells and aging.
Ovadya Y, Landsberger T, Leins H, Vadai E, Gal H, Biran A, Yosef R, Sagiv A, Agrawal A, Shapira A, Windheim J, Tsoory M, Schirmbeck R, Amit I, Geiger H, Krizhanovsky V. Ovadya Y, et al. Among authors: biran a. Nat Commun. 2018 Dec 21;9(1):5435. doi: 10.1038/s41467-018-07825-3. Nat Commun. 2018. PMID: 30575733 Free PMC article.
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Yosef R, Pilpel N, Tokarsky-Amiel R, Biran A, Ovadya Y, Cohen S, Vadai E, Dassa L, Shahar E, Condiotti R, Ben-Porath I, Krizhanovsky V. Yosef R, et al. Among authors: biran a. Nat Commun. 2016 Apr 6;7:11190. doi: 10.1038/ncomms11190. Nat Commun. 2016. PMID: 27048913 Free PMC article.
Senescent cells communicate via intercellular protein transfer.
Biran A, Perelmutter M, Gal H, Burton DG, Ovadya Y, Vadai E, Geiger T, Krizhanovsky V. Biran A, et al. Genes Dev. 2015 Apr 15;29(8):791-802. doi: 10.1101/gad.259341.115. Epub 2015 Apr 8. Genes Dev. 2015. PMID: 25854920 Free PMC article.
Senescent cells talk frankly with their neighbors.
Biran A, Krizhanovsky V. Biran A, et al. Cell Cycle. 2015;14(14):2181-2. doi: 10.1080/15384101.2015.1056608. Epub 2015 Jun 1. Cell Cycle. 2015. PMID: 26030140 Free PMC article. No abstract available.
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.
Guièze R, Liu VM, Rosebrock D, Jourdain AA, Hernández-Sánchez M, Martinez Zurita A, Sun J, Ten Hacken E, Baranowski K, Thompson PA, Heo JM, Cartun Z, Aygün O, Iorgulescu JB, Zhang W, Notarangelo G, Livitz D, Li S, Davids MS, Biran A, Fernandes SM, Brown JR, Lako A, Ciantra ZB, Lawlor MA, Keskin DB, Udeshi ND, Wierda WG, Livak KJ, Letai AG, Neuberg D, Harper JW, Carr SA, Piccioni F, Ott CJ, Leshchiner I, Johannessen CM, Doench J, Mootha VK, Getz G, Wu CJ. Guièze R, et al. Among authors: biran a. Cancer Cell. 2019 Oct 14;36(4):369-384.e13. doi: 10.1016/j.ccell.2019.08.005. Epub 2019 Sep 19. Cancer Cell. 2019. PMID: 31543463 Free PMC article.
76 results