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Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.
Pelczar P, Zibat A, van Dop WA, Heijmans J, Bleckmann A, Gruber W, Nitzki F, Uhmann A, Guijarro MV, Hernando E, Dittmann K, Wienands J, Dressel R, Wojnowski L, Binder C, Taguchi T, Beissbarth T, Hogendoorn PC, Antonescu CR, Rubin BP, Schulz-Schaeffer W, Aberger F, van den Brink GR, Hahn H. Pelczar P, et al. Among authors: binder c. Gastroenterology. 2013 Jan;144(1):134-144.e6. doi: 10.1053/j.gastro.2012.09.061. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041331 Free PMC article.
The Hedgehog receptor Patched controls lymphoid lineage commitment.
Uhmann A, Dittmann K, Nitzki F, Dressel R, Koleva M, Frommhold A, Zibat A, Binder C, Adham I, Nitsche M, Heller T, Armstrong V, Schulz-Schaeffer W, Wienands J, Hahn H. Uhmann A, et al. Among authors: binder c. Blood. 2007 Sep 15;110(6):1814-23. doi: 10.1182/blood-2007-02-075648. Epub 2007 May 29. Blood. 2007. PMID: 17536012 Free article.
T cell development critically depends on prethymic stromal patched expression.
Uhmann A, van den Brandt J, Dittmann K, Hess I, Dressel R, Binder C, Lühder F, Christiansen H, Fassnacht M, Bhandoola A, Wienands J, Reichardt HM, Hahn H. Uhmann A, et al. Among authors: binder c. J Immunol. 2011 Mar 15;186(6):3383-91. doi: 10.4049/jimmunol.1001939. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317383
Ror2 Signaling and Its Relevance in Breast Cancer Progression.
Bayerlová M, Menck K, Klemm F, Wolff A, Pukrop T, Binder C, Beißbarth T, Bleckmann A. Bayerlová M, et al. Among authors: binder c. Front Oncol. 2017 Jun 26;7:135. doi: 10.3389/fonc.2017.00135. eCollection 2017. Front Oncol. 2017. PMID: 28695110 Free PMC article.
Microvesicles in Cancer: Small Size, Large Potential.
Menck K, Sivaloganathan S, Bleckmann A, Binder C. Menck K, et al. Among authors: binder c. Int J Mol Sci. 2020 Jul 28;21(15):5373. doi: 10.3390/ijms21155373. Int J Mol Sci. 2020. PMID: 32731639 Free PMC article. Review.
β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases.
Bleckmann A, Conradi LC, Menck K, Schmick NA, Schubert A, Rietkötter E, Arackal J, Middel P, Schambony A, Liersch T, Homayounfar K, Beißbarth T, Klemm F, Binder C, Pukrop T. Bleckmann A, et al. Among authors: binder c. Clin Exp Metastasis. 2016 Apr;33(4):309-23. doi: 10.1007/s10585-016-9780-3. Epub 2016 Feb 9. Clin Exp Metastasis. 2016. PMID: 26862065 Free PMC article.
746 results