Synthetic phage-based approach for sensitive and specific detection of Escherichia coli O157.
Tamura A, Azam AH, Nakamura T, Lee K, Iyoda S, Kondo K, Ojima S, Chihara K, Yamashita W, Cui L, Akeda Y, Watashi K, Takahashi Y, Yotsuyanagi H, Kiga K.
Tamura A, et al.
Commun Biol. 2024 May 6;7(1):535. doi: 10.1038/s42003-024-06247-w.
Commun Biol. 2024.
PMID: 38710842
Free PMC article.
Although phage-based detection methods for E. coli O157 are being explored, research on their specificity with clinical isolates is lacking. Here, we describe an in vitro assembly-based synthesis of vB_Eco4M-7, an O157 antigen-specific phage with a 68-kb genome, and its us …
Although phage-based detection methods for E. coli O157 are being explored, research on their specificity with clinical isolates is l …