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Pig kidney xenotransplantation: Progress toward clinical trials.
Cooper DKC, Hara H, Iwase H, Yamamoto T, Wang ZY, Jagdale A, Bikhet MH, Nguyen HQ, Foote JB, Paris WD, Ayares D, Kumar V, Anderson DJ, Locke JE, Eckhoff DE. Cooper DKC, et al. Among authors: bikhet mh. Clin Transplant. 2021 Jan;35(1):e14139. doi: 10.1111/ctr.14139. Epub 2020 Nov 19. Clin Transplant. 2021. PMID: 33131148 Review.
The final obstacle to successful pre-clinical xenotransplantation?
Yamamoto T, Hara H, Iwase H, Jagdale A, Bikhet MH, Morsi MA, Cui Y, Nguyen HQ, Wang ZY, Anderson DJ, Foote J, Schuurman HJ, Ayares D, Eckhoff DE, Cooper DKC. Yamamoto T, et al. Among authors: bikhet mh. Xenotransplantation. 2020 Sep;27(5):e12596. doi: 10.1111/xen.12596. Epub 2020 Jun 25. Xenotransplantation. 2020. PMID: 32585053
Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons.
Iwase H, Jagdale A, Yamamoto T, Bikhet MH, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Eckhoff DE, Foote JB, Fatima H, Schuurman HJ, Hara H, Cooper DKC. Iwase H, et al. Among authors: bikhet mh. Xenotransplantation. 2021 Jul;28(4):e12700. doi: 10.1111/xen.12700. Epub 2021 May 25. Xenotransplantation. 2021. PMID: 34036638
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.
Foote JB, Jagdale A, Yamamoto T, Hara H, Bikhet MH, Schuurman HJ, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Fatima H, Eckhoff DE, Cooper DKC, Iwase H. Foote JB, et al. Among authors: bikhet mh. Xenotransplantation. 2021 Nov;28(6):e12715. doi: 10.1111/xen.12715. Epub 2021 Oct 13. Xenotransplantation. 2021. PMID: 34644438 Free PMC article.
Cardiac and Pulmonary Histopathology in Baboons Following Genetically-Engineered Pig Orthotopic Heart Transplantation.
Litovsky SH, Foote JB, Jagdale A, Walcott G, Iwase H, Bikhet MH, Yamamoto T, Hansen-Estruch C, Ezzelarab MB, Ayares D, Carlo WF, Rhodes LA, Crawford JH, Borasino S, Dabal RJ, Padilla LA, Hara H, Cooper DKC, Cleveland DC. Litovsky SH, et al. Among authors: bikhet mh. Ann Transplant. 2022 Jul 5;27:e935338. doi: 10.12659/AOT.935338. Ann Transplant. 2022. PMID: 35789146 Free PMC article.
Observations on hydronephrosis after pig kidney transplantation in baboons.
Foote JB, Bikhet MH, Hansen-Estruch C, Javed M, Ayares D, Hara H, Humar A, Eckhoff DE, Cooper DKC. Foote JB, et al. Among authors: bikhet mh. Xenotransplantation. 2022 Nov;29(6):e12779. doi: 10.1111/xen.12779. Epub 2022 Sep 25. Xenotransplantation. 2022. PMID: 36156826 Free PMC article.
The immune system in infants: Relevance to xenotransplantation.
Bikhet M, Morsi M, Hara H, Rhodes LA, Carlo WF, Cleveland D, Cooper DKC, Iwase H. Bikhet M, et al. Pediatr Transplant. 2020 Nov;24(7):e13795. doi: 10.1111/petr.13795. Epub 2020 Aug 26. Pediatr Transplant. 2020. PMID: 32845539 Free PMC article. Review.
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