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Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics.
Taiarol L, Bigogno C, Sesana S, Kravicz M, Viale F, Pozzi E, Monza L, Carozzi VA, Meregalli C, Valtorta S, Moresco RM, Koch M, Barbugian F, Russo L, Dondio G, Steinkühler C, Re F. Taiarol L, et al. Among authors: bigogno c. Cancers (Basel). 2022 Jun 16;14(12):2978. doi: 10.3390/cancers14122978. Cancers (Basel). 2022. PMID: 35740641 Free PMC article.
Discovery, synthesis, and pharmacological evaluation of spiropiperidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors.
Varasi M, Thaler F, Abate A, Bigogno C, Boggio R, Carenzi G, Cataudella T, Dal Zuffo R, Fulco MC, Rozio MG, Mai A, Dondio G, Minucci S, Mercurio C. Varasi M, et al. Among authors: bigogno c. J Med Chem. 2011 Apr 28;54(8):3051-64. doi: 10.1021/jm200146u. Epub 2011 Apr 1. J Med Chem. 2011. PMID: 21417419
Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.
Marra A, Rossi D, Pignataro L, Bigogno C, Canta A, Oggioni N, Malacrida A, Corbo M, Cavaletti G, Peviani M, Curti D, Dondio G, Collina S. Marra A, et al. Among authors: bigogno c. Future Med Chem. 2016;8(3):287-95. doi: 10.4155/fmc.15.191. Epub 2016 Feb 22. Future Med Chem. 2016. PMID: 26898712
Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.
Tesei A, Cortesi M, Pignatta S, Arienti C, Dondio GM, Bigogno C, Malacrida A, Miloso M, Meregalli C, Chiorazzi A, Carozzi V, Cavaletti G, Rui M, Marra A, Rossi D, Collina S. Tesei A, et al. Among authors: bigogno c. Front Pharmacol. 2019 May 14;10:490. doi: 10.3389/fphar.2019.00490. eCollection 2019. Front Pharmacol. 2019. PMID: 31156430 Free PMC article.
Synthesis and biological characterization of spiro[2H-(1,3)-benzoxazine-2,4'-piperidine] based histone deacetylase inhibitors.
Thaler F, Varasi M, Abate A, Carenzi G, Colombo A, Bigogno C, Boggio R, Zuffo RD, Rapetti D, Resconi A, Regalia N, Vultaggio S, Dondio G, Gagliardi S, Minucci S, Mercurio C. Thaler F, et al. Among authors: bigogno c. Eur J Med Chem. 2013 Jun;64:273-84. doi: 10.1016/j.ejmech.2013.03.061. Epub 2013 Apr 10. Eur J Med Chem. 2013. PMID: 23644210
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.
Basilico N, Parapini S, Sparatore A, Romeo S, Misiano P, Vivas L, Yardley V, Croft SL, Habluetzel A, Lucantoni L, Renia L, Russell B, Suwanarusk R, Nosten F, Dondio G, Bigogno C, Jabes D, Taramelli D. Basilico N, et al. Among authors: bigogno c. Molecules. 2017 Dec 1;22(12):2102. doi: 10.3390/molecules22122102. Molecules. 2017. PMID: 29194347 Free PMC article.
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