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What's new on CDC25 phosphatase inhibitors.
Contour-Galcera MO, Sidhu A, Prévost G, Bigg D, Ducommun B. Contour-Galcera MO, et al. Among authors: bigg d. Pharmacol Ther. 2007 Jul;115(1):1-12. doi: 10.1016/j.pharmthera.2007.03.009. Epub 2007 Apr 21. Pharmacol Ther. 2007. PMID: 17531323 Review.
IRC-083927 is a new tubulin binder that inhibits growth of human tumor cells resistant to standard tubulin-binding agents.
Liberatore AM, Coulomb H, Pons D, Dutruel O, Kasprzyk PG, Carlson M, Nelson AS, Newman SP, Stengel C, Auvray P, Hesry V, Foll B, Narboux N, Morlais D, Le Moing M, Bernetiere S, Dellile R, Camara J, Ferrandis E, Bigg DC, Prévost GP. Liberatore AM, et al. Among authors: bigg dc. Mol Cancer Ther. 2008 Aug;7(8):2426-34. doi: 10.1158/1535-7163.MCT-08-0208. Mol Cancer Ther. 2008. PMID: 18723488
Synthesis and bioevaluation of 22-hydroxyacuminatine analogs.
Grillet F, Baumlová B, Prévost G, Constant JF, Chaumeron S, Bigg DC, Greene AE, Kanazawa A. Grillet F, et al. Among authors: bigg dc. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2143-6. doi: 10.1016/j.bmcl.2008.01.082. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18276141
Novel dual inhibitors of calpain and lipid peroxidation.
Auvin S, Pignol B, Navet E, Pons D, Marin JG, Bigg D, Chabrier PE. Auvin S, et al. Among authors: bigg d. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3825-8. doi: 10.1016/j.bmcl.2004.04.105. Bioorg Med Chem Lett. 2004. PMID: 15203170
46 results