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Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Biering SB, Akey DL, Wong MP, Brown WC, Lo NTN, Puerta-Guardo H, Tramontini Gomes de Sousa F, Wang C, Konwerski JR, Espinosa DA, Bockhaus NJ, Glasner DR, Li J, Blanc SF, Juan EY, Elledge SJ, Mina MJ, Beatty PR, Smith JL, Harris E. Biering SB, et al. Science. 2021 Jan 8;371(6525):194-200. doi: 10.1126/science.abc0476. Science. 2021. PMID: 33414220 Free PMC article.
Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation.
Wang C, Puerta-Guardo H, Biering SB, Glasner DR, Tran EB, Patana M, Gomberg TA, Malvar C, Lo NTN, Espinosa DA, Harris E. Wang C, et al. Among authors: biering sb. PLoS Pathog. 2019 Jul 29;15(7):e1007938. doi: 10.1371/journal.ppat.1007938. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31356638 Free PMC article.
Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies.
Young E, Carnahan RH, Andrade DV, Kose N, Nargi RS, Fritch EJ, Munt JE, Doyle MP, White L, Baric TJ, Stoops M, DeSilva A, Tse LV, Martinez DR, Zhu D, Metz S, Wong MP, Espinosa DA, Montoya M, Biering SB, Sukulpolvi-Petty S, Kuan G, Balmaseda A, Diamond MS, Harris E, Crowe JE Jr, Baric RS. Young E, et al. Among authors: biering sb. Cell Host Microbe. 2020 May 13;27(5):710-724.e7. doi: 10.1016/j.chom.2020.04.007. Cell Host Microbe. 2020. PMID: 32407709 Free PMC article.
Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain.
Wessel AW, Dowd KA, Biering SB, Zhang P, Edeling MA, Nelson CA, Funk KE, DeMaso CR, Klein RS, Smith JL, Cao TM, Kuhn RJ, Fremont DH, Harris E, Pierson TC, Diamond MS. Wessel AW, et al. Among authors: biering sb. J Virol. 2021 Sep 27;95(20):e0084421. doi: 10.1128/JVI.00844-21. Epub 2021 Aug 4. J Virol. 2021. PMID: 34346770 Free PMC article.
The Compound SBI-0090799 Inhibits Zika Virus Infection by Blocking De Novo Formation of the Membranous Replication Compartment.
Riva L, Goellner S, Biering SB, Huang CT, Rubanov AN, Haselmann U, Warnes CM, De Jesus PD, Martin-Sancho L, Terskikh AV, Harris E, Pinkerton AB, Bartenschlager R, Chanda SK. Riva L, et al. Among authors: biering sb. J Virol. 2021 Oct 27;95(22):e0099621. doi: 10.1128/JVI.00996-21. Epub 2021 Sep 1. J Virol. 2021. PMID: 34468177 Free PMC article.
A step towards therapeutics for dengue.
Biering SB, Harris E. Biering SB, et al. Nature. 2021 Oct;598(7881):420-421. doi: 10.1038/d41586-021-02638-9. Nature. 2021. PMID: 34616083 No abstract available.
One antibody to treat them all.
Biering SB. Biering SB. Science. 2022 Feb 25;375(6583):803. doi: 10.1126/science.abn9651. Epub 2022 Feb 24. Science. 2022. PMID: 35201864 Free article.
44 results