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Spatial transcriptomics at subspot resolution with BayesSpace.
Zhao E, Stone MR, Ren X, Guenthoer J, Smythe KS, Pulliam T, Williams SR, Uytingco CR, Taylor SEB, Nghiem P, Bielas JH, Gottardo R. Zhao E, et al. Among authors: bielas jh. Nat Biotechnol. 2021 Nov;39(11):1375-1384. doi: 10.1038/s41587-021-00935-2. Epub 2021 Jun 3. Nat Biotechnol. 2021. PMID: 34083791 Free PMC article.
Digital genomic quantification of tumor-infiltrating lymphocytes.
Robins HS, Ericson NG, Guenthoer J, O'Briant KC, Tewari M, Drescher CW, Bielas JH. Robins HS, et al. Among authors: bielas jh. Sci Transl Med. 2013 Dec 4;5(214):214ra169. doi: 10.1126/scitranslmed.3007247. Sci Transl Med. 2013. PMID: 24307693 Free PMC article.
Massively parallel digital transcriptional profiling of single cells.
Zheng GX, Terry JM, Belgrader P, Ryvkin P, Bent ZW, Wilson R, Ziraldo SB, Wheeler TD, McDermott GP, Zhu J, Gregory MT, Shuga J, Montesclaros L, Underwood JG, Masquelier DA, Nishimura SY, Schnall-Levin M, Wyatt PW, Hindson CM, Bharadwaj R, Wong A, Ness KD, Beppu LW, Deeg HJ, McFarland C, Loeb KR, Valente WJ, Ericson NG, Stevens EA, Radich JP, Mikkelsen TS, Hindson BJ, Bielas JH. Zheng GX, et al. Among authors: bielas jh. Nat Commun. 2017 Jan 16;8:14049. doi: 10.1038/ncomms14049. Nat Commun. 2017. PMID: 28091601 Free PMC article.
Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA.
Paulson KG, Voillet V, McAfee MS, Hunter DS, Wagener FD, Perdicchio M, Valente WJ, Koelle SJ, Church CD, Vandeven N, Thomas H, Colunga AG, Iyer JG, Yee C, Kulikauskas R, Koelle DM, Pierce RH, Bielas JH, Greenberg PD, Bhatia S, Gottardo R, Nghiem P, Chapuis AG. Paulson KG, et al. Among authors: bielas jh. Nat Commun. 2018 Sep 24;9(1):3868. doi: 10.1038/s41467-018-06300-3. Nat Commun. 2018. PMID: 30250229 Free PMC article.
Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency.
Lahman MC, Schmitt TM, Paulson KG, Vigneron N, Buenrostro D, Wagener FD, Voillet V, Martin L, Gottardo R, Bielas J, McElrath JM, Stirewalt DL, Pogosova-Agadjanyan EL, Yeung CC, Pierce RH, Egan DN, Bar M, Hendrie PC, Kinsella S, Vakil A, Butler J, Chaffee M, Linton J, McAfee MS, Hunter DS, Bleakley M, Rongvaux A, Van den Eynde BJ, Chapuis AG, Greenberg PD. Lahman MC, et al. Sci Transl Med. 2022 Feb 9;14(631):eabg8070. doi: 10.1126/scitranslmed.abg8070. Epub 2022 Feb 9. Sci Transl Med. 2022. PMID: 35138909 Free PMC article.
An In Vivo Model of Human Macrophages in Metastatic Melanoma.
Voillet V, Berger TR, McKenna KM, Paulson KG, Tan WH, Smythe KS, Hunter DS, Valente WJ, Weaver S, Campbell JS, Kim TS, Byrd DR, Bielas JH, Pierce RH, Chapuis AG, Gottardo R, Rongvaux A. Voillet V, et al. Among authors: bielas jh. J Immunol. 2022 Aug 1;209(3):606-620. doi: 10.4049/jimmunol.2101109. Epub 2022 Jul 11. J Immunol. 2022. PMID: 35817516 Free PMC article.
Defining cellular population dynamics at single-cell resolution during prostate cancer progression.
Germanos AA, Arora S, Zheng Y, Goddard ET, Coleman IM, Ku AT, Wilkinson S, Song H, Brady NJ, Amezquita RA, Zager M, Long A, Yang YC, Bielas JH, Gottardo R, Rickman DS, Huang FW, Ghajar CM, Nelson PS, Sowalsky AG, Setty M, Hsieh AC. Germanos AA, et al. Among authors: bielas jh. Elife. 2022 Dec 13;11:e79076. doi: 10.7554/eLife.79076. Elife. 2022. PMID: 36511483 Free PMC article.
Quantification of random genomic mutations.
Bielas JH, Loeb LA. Bielas JH, et al. Nat Methods. 2005 Apr;2(4):285-90. doi: 10.1038/nmeth751. Epub 2005 Mar 23. Nat Methods. 2005. PMID: 15782221
Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics.
Rose JC, Stephany JJ, Valente WJ, Trevillian BM, Dang HV, Bielas JH, Maly DJ, Fowler DM. Rose JC, et al. Among authors: bielas jh. Nat Methods. 2017 Sep;14(9):891-896. doi: 10.1038/nmeth.4368. Epub 2017 Jul 24. Nat Methods. 2017. PMID: 28737741 Free PMC article.
54 results