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Could drugs inhibiting the mevalonate pathway also target cancer stem cells?
Likus W, Siemianowicz K, Bieńk K, Pakuła M, Pathak H, Dutta C, Wang Q, Shojaei S, Assaraf YG, Ghavami S, Cieślar-Pobuda A, Łos MJ. Likus W, et al. Among authors: bienk k. Drug Resist Updat. 2016 Mar;25:13-25. doi: 10.1016/j.drup.2016.02.001. Epub 2016 Feb 20. Drug Resist Updat. 2016. PMID: 27155373 Free article. Review.
An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications.
Kuhlmann M, Hamming JBR, Voldum A, Tsakiridou G, Larsen MT, Schmøkel JS, Sohn E, Bienk K, Schaffert D, Sørensen ES, Wengel J, Dupont DM, Howard KA. Kuhlmann M, et al. Among authors: bienk k. Mol Ther Nucleic Acids. 2017 Dec 15;9:284-293. doi: 10.1016/j.omtn.2017.10.004. Epub 2017 Oct 7. Mol Ther Nucleic Acids. 2017. PMID: 29246307 Free PMC article.
Mutants and molecular dockings reveal that the primary L-thyroxine binding site in human serum albumin is not the one which can cause familial dysalbuminemic hyperthyroxinemia.
Kragh-Hansen U, Minchiotti L, Coletta A, Bienk K, Galliano M, Schiøtt B, Iwao Y, Ishima Y, Otagiri M. Kragh-Hansen U, et al. Among authors: bienk k. Biochim Biophys Acta. 2016 Apr;1860(4):648-60. doi: 10.1016/j.bbagen.2016.01.001. Epub 2016 Jan 8. Biochim Biophys Acta. 2016. PMID: 26777880