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Could drugs inhibiting the mevalonate pathway also target cancer stem cells?
Drug Resist Updat. 2016 Mar;25:13-25. doi: 10.1016/j.drup.2016.02.001. Epub 2016 Feb 20.
Drug Resist Updat. 2016.
PMID: 27155373
Free article.
Review.
An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing.
Bienk K, Hvam ML, Pakula MM, Dagnæs-Hansen F, Wengel J, Malle BM, Kragh-Hansen U, Cameron J, Bukrinski JT, Howard KA.
Bienk K, et al.
J Control Release. 2016 Jun 28;232:143-51. doi: 10.1016/j.jconrel.2016.04.013. Epub 2016 Apr 12.
J Control Release. 2016.
PMID: 27084489
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Extended blood circulation and joint accumulation of a p(HPMA-co-AzMA)-based nanoconjugate in a murine model of rheumatoid arthritis.
Ebbesen MF, Bienk K, Deleuran BW, Howard KA.
Ebbesen MF, et al. Among authors: bienk k.
Mol Cell Ther. 2014 Sep 11;2:29. doi: 10.1186/2052-8426-2-29. eCollection 2014.
Mol Cell Ther. 2014.
PMID: 26056596
Free PMC article.
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Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications.
Hansen IM, Ebbesen MF, Kaspersen L, Thomsen T, Bienk K, Cai Y, Malle BM, Howard KA.
Hansen IM, et al. Among authors: bienk k.
Mol Pharm. 2017 Jul 3;14(7):2359-2367. doi: 10.1021/acs.molpharmaceut.7b00236. Epub 2017 May 26.
Mol Pharm. 2017.
PMID: 28499338
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An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications.
Kuhlmann M, Hamming JBR, Voldum A, Tsakiridou G, Larsen MT, Schmøkel JS, Sohn E, Bienk K, Schaffert D, Sørensen ES, Wengel J, Dupont DM, Howard KA.
Kuhlmann M, et al. Among authors: bienk k.
Mol Ther Nucleic Acids. 2017 Dec 15;9:284-293. doi: 10.1016/j.omtn.2017.10.004. Epub 2017 Oct 7.
Mol Ther Nucleic Acids. 2017.
PMID: 29246307
Free PMC article.
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Mutants and molecular dockings reveal that the primary L-thyroxine binding site in human serum albumin is not the one which can cause familial dysalbuminemic hyperthyroxinemia.
Kragh-Hansen U, Minchiotti L, Coletta A, Bienk K, Galliano M, Schiøtt B, Iwao Y, Ishima Y, Otagiri M.
Kragh-Hansen U, et al. Among authors: bienk k.
Biochim Biophys Acta. 2016 Apr;1860(4):648-60. doi: 10.1016/j.bbagen.2016.01.001. Epub 2016 Jan 8.
Biochim Biophys Acta. 2016.
PMID: 26777880
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