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Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.
Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A, Bicciato S, Tripodo C, Mantovani F, Del Sal G. Capaci V, et al. Among authors: bicciato s. Nat Commun. 2020 Aug 7;11(1):3945. doi: 10.1038/s41467-020-17596-5. Nat Commun. 2020. PMID: 32770028 Free PMC article.
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis.
Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B, Solari A, Bobisse S, Rondina MB, Guzzardo V, Parenti AR, Rosato A, Bicciato S, Balmain A, Piccolo S. Adorno M, et al. Among authors: bicciato s. Cell. 2009 Apr 3;137(1):87-98. doi: 10.1016/j.cell.2009.01.039. Cell. 2009. PMID: 19345189 Free article.
A MicroRNA targeting dicer for metastasis control.
Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, Enzo E, Guzzardo V, Rondina M, Spruce T, Parenti AR, Daidone MG, Bicciato S, Piccolo S. Martello G, et al. Among authors: bicciato s. Cell. 2010 Jun 25;141(7):1195-207. doi: 10.1016/j.cell.2010.05.017. Cell. 2010. PMID: 20603000 Free article.
Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.
Rustighi A, Zannini A, Tiberi L, Sommaggio R, Piazza S, Sorrentino G, Nuzzo S, Tuscano A, Eterno V, Benvenuti F, Santarpia L, Aifantis I, Rosato A, Bicciato S, Zambelli A, Del Sal G. Rustighi A, et al. Among authors: bicciato s. EMBO Mol Med. 2014 Jan;6(1):99-119. doi: 10.1002/emmm.201302909. Epub 2013 Dec 15. EMBO Mol Med. 2014. PMID: 24357640 Free PMC article.
Notch is a direct negative regulator of the DNA-damage response.
Vermezovic J, Adamowicz M, Santarpia L, Rustighi A, Forcato M, Lucano C, Massimiliano L, Costanzo V, Bicciato S, Del Sal G, d'Adda di Fagagna F. Vermezovic J, et al. Among authors: bicciato s. Nat Struct Mol Biol. 2015 May;22(5):417-24. doi: 10.1038/nsmb.3013. Epub 2015 Apr 20. Nat Struct Mol Biol. 2015. PMID: 25895060 Free article.
YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins.
Di Agostino S, Sorrentino G, Ingallina E, Valenti F, Ferraiuolo M, Bicciato S, Piazza S, Strano S, Del Sal G, Blandino G. Di Agostino S, et al. Among authors: bicciato s. EMBO Rep. 2016 Feb;17(2):188-201. doi: 10.15252/embr.201540488. Epub 2015 Dec 21. EMBO Rep. 2016. PMID: 26691213 Free PMC article.
193 results