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Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer.
Singhal S, Bhojnagarwala PS, O'Brien S, Moon EK, Garfall AL, Rao AS, Quatromoni JG, Stephen TL, Litzky L, Deshpande C, Feldman MD, Hancock WW, Conejo-Garcia JR, Albelda SM, Eruslanov EB. Singhal S, et al. Among authors: bhojnagarwala ps. Cancer Cell. 2016 Jul 11;30(1):120-135. doi: 10.1016/j.ccell.2016.06.001. Epub 2016 Jun 30. Cancer Cell. 2016. PMID: 27374224 Free PMC article.
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer.
Eruslanov EB, Bhojnagarwala PS, Quatromoni JG, Stephen TL, Ranganathan A, Deshpande C, Akimova T, Vachani A, Litzky L, Hancock WW, Conejo-Garcia JR, Feldman M, Albelda SM, Singhal S. Eruslanov EB, et al. Among authors: bhojnagarwala ps. J Clin Invest. 2014 Dec;124(12):5466-80. doi: 10.1172/JCI77053. Epub 2014 Nov 10. J Clin Invest. 2014. PMID: 25384214 Free PMC article. Clinical Trial.
Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms.
Negorev D, Beier UH, Zhang T, Quatromoni JG, Bhojnagarwala P, Albelda SM, Singhal S, Eruslanov E, Lohoff FW, Levine MH, Diamond JM, Christie JD, Hancock WW, Akimova T. Negorev D, et al. Sci Rep. 2018 Feb 16;8(1):3135. doi: 10.1038/s41598-018-21450-6. Sci Rep. 2018. PMID: 29453429 Free PMC article.
Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer.
Singhal S, Stadanlick J, Annunziata MJ, Rao AS, Bhojnagarwala PS, O'Brien S, Moon EK, Cantu E, Danet-Desnoyers G, Ra HJ, Litzky L, Akimova T, Beier UH, Hancock WW, Albelda SM, Eruslanov EB. Singhal S, et al. Among authors: bhojnagarwala ps. Sci Transl Med. 2019 Feb 13;11(479):eaat1500. doi: 10.1126/scitranslmed.aat1500. Sci Transl Med. 2019. PMID: 30760579 Free PMC article.
DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas.
Zhu X, Perales-Puchalt A, Wojtak K, Xu Z, Yun K, Bhojnagarwala PS, Bordoloi D, Park DH, Liaw K, Bah MA, Lieberman PM, Gary EN, Patel A, Weiner DB. Zhu X, et al. Among authors: bhojnagarwala ps. Mol Ther Oncolytics. 2021 Dec 21;24:218-229. doi: 10.1016/j.omto.2021.12.017. eCollection 2022 Mar 17. Mol Ther Oncolytics. 2021. PMID: 35071745 Free PMC article.
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