Beyer M - Search Results

1

Histone deacetylase inhibitors modulate hormesis in leukemic cells with mutant FMS-like tyrosine kinase-3.

Zeyn Y, Hausmann K, Halilovic M, Beyer M, Ibrahim HS, Brenner W, Mahboobi S, Bros M, Sippl W, Krämer OH. Zeyn Y, et al. Among authors: beyer m. Leukemia. 2023 Nov;37(11):2319-2323. doi: 10.1038/s41375-023-02036-2. Epub 2023 Sep 21. Leukemia. 2023. PMID: 37735559 Free PMC article. No abstract available.

2

Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.

Beyer M, Henninger SJ, Haehnel PS, Mustafa AM, Gurdal E, Schubert B, Christmann M, Sellmer A, Mahboobi S, Drube S, Sippl W, Kindler T, Krämer OH. Beyer M, et al. Cell Chem Biol. 2022 Mar 17;29(3):398-411.e4. doi: 10.1016/j.chembiol.2021.10.011. Epub 2021 Nov 10. Cell Chem Biol. 2022. PMID: 34762849 Free article.

3

How to Distinguish Between the Activity of HDAC1-3 and HDAC6 with Western Blot.

Beyer M, Kiweler N, Mahboobi S, Krämer OH. Beyer M, et al. Methods Mol Biol. 2017;1510:355-364. doi: 10.1007/978-1-4939-6527-4_26. Methods Mol Biol. 2017. PMID: 27761834

4

Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.

Leonhardt M, Sellmer A, Krämer OH, Dove S, Elz S, Kraus B, Beyer M, Mahboobi S. Leonhardt M, et al. Among authors: beyer m. Eur J Med Chem. 2018 May 25;152:329-357. doi: 10.1016/j.ejmech.2018.04.046. Epub 2018 Apr 26. Eur J Med Chem. 2018. PMID: 29738953

5

Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3.

Wachholz V, Mustafa AM, Zeyn Y, Henninger SJ, Beyer M, Dzulko M, Piée-Staffa A, Brachetti C, Haehnel PS, Sellmer A, Mahboobi S, Kindler T, Brenner W, Nikolova T, Krämer OH. Wachholz V, et al. Among authors: beyer m. Arch Toxicol. 2022 Jan;96(1):177-193. doi: 10.1007/s00204-021-03174-1. Epub 2021 Oct 19. Arch Toxicol. 2022. PMID: 34665271 Free PMC article.

6

RNA interference protocol to silence oncogenic drivers in leukemia cell lines.

Beyer M, Krämer OH. Beyer M, et al. STAR Protoc. 2022 Sep 16;3(3):101512. doi: 10.1016/j.xpro.2022.101512. Epub 2022 Jul 1. STAR Protoc. 2022. PMID: 35779262 Free PMC article.

7

News and views : AUTOTACs join the arena for targeted protein degradation.

Mieland AO, Beyer M, Krämer OH. Mieland AO, et al. Among authors: beyer m. Arch Toxicol. 2022 Jul;96(7):2143-2144. doi: 10.1007/s00204-022-03312-3. Epub 2022 May 17. Arch Toxicol. 2022. PMID: 35577987 Free PMC article. No abstract available.

8

Human platelet lysate as validated replacement for animal serum to assess chemosensitivity.

Pons M, Nagel G, Zeyn Y, Beyer M, Laguna T, Brachetti T, Sellmer A, Mahboobi S, Conradi R, Butter F, Krämer OH. Pons M, et al. Among authors: beyer m. ALTEX. 2019;36(2):277-288. doi: 10.14573/altex.1809211. Epub 2018 Dec 14. ALTEX. 2019. PMID: 30570667 Free article.

9

Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.

Sellmer A, Stangl H, Beyer M, Grünstein E, Leonhardt M, Pongratz H, Eichhorn E, Elz S, Striegl B, Jenei-Lanzl Z, Dove S, Straub RH, Krämer OH, Mahboobi S. Sellmer A, et al. Among authors: beyer m. J Med Chem. 2018 Apr 26;61(8):3454-3477. doi: 10.1021/acs.jmedchem.7b01593. Epub 2018 Apr 6. J Med Chem. 2018. PMID: 29589441

10

A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.

Sellmer A, Pilsl B, Beyer M, Pongratz H, Wirth L, Elz S, Dove S, Henninger SJ, Spiekermann K, Polzer H, Klaeger S, Kuster B, Böhmer FD, Fiebig HH, Krämer OH, Mahboobi S. Sellmer A, et al. Among authors: beyer m. Eur J Med Chem. 2020 May 1;193:112232. doi: 10.1016/j.ejmech.2020.112232. Epub 2020 Mar 13. Eur J Med Chem. 2020. PMID: 32199135

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