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Patient-derived xenografts as preclinical neuroblastoma models.
Braekeveldt N, Bexell D. Braekeveldt N, et al. Among authors: bexell d. Cell Tissue Res. 2018 May;372(2):233-243. doi: 10.1007/s00441-017-2687-8. Epub 2017 Sep 19. Cell Tissue Res. 2018. PMID: 28924803 Free PMC article. Review.
Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma.
Braekeveldt N, von Stedingk K, Fransson S, Martinez-Monleon A, Lindgren D, Axelson H, Levander F, Willforss J, Hansson K, Øra I, Backman T, Börjesson A, Beckman S, Esfandyari J, Berbegall AP, Noguera R, Karlsson J, Koster J, Martinsson T, Gisselsson D, Påhlman S, Bexell D. Braekeveldt N, et al. Among authors: bexell d. Cancer Res. 2018 Oct 15;78(20):5958-5969. doi: 10.1158/0008-5472.CAN-18-0527. Epub 2018 Aug 28. Cancer Res. 2018. PMID: 30154149
Engineered human mesenchymal stem cells for neuroblastoma therapeutics.
Nieddu V, Piredda R, Bexell D, Barton J, Anderson J, Sebire N, Kolluri K, Janes SM, Karteris E, Sala A. Nieddu V, et al. Among authors: bexell d. Oncol Rep. 2019 Jul;42(1):35-42. doi: 10.3892/or.2019.7152. Epub 2019 May 8. Oncol Rep. 2019. PMID: 31115546 Free PMC article.
Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma.
Mohlin S, Hansson K, Radke K, Martinez S, Blanco-Apiricio C, Garcia-Ruiz C, Welinder C, Esfandyari J, O'Neill M, Pastor J, von Stedingk K, Bexell D. Mohlin S, et al. Among authors: bexell d. EMBO Mol Med. 2019 Aug;11(8):e10058. doi: 10.15252/emmm.201810058. Epub 2019 Jul 16. EMBO Mol Med. 2019. PMID: 31310053 Free PMC article.
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma.
Hansson K, Radke K, Aaltonen K, Saarela J, Mañas A, Sjölund J, Smith EM, Pietras K, Påhlman S, Wennerberg K, Gisselsson D, Bexell D. Hansson K, et al. Among authors: bexell d. Sci Transl Med. 2020 Sep 23;12(562):eaba4434. doi: 10.1126/scitranslmed.aba4434. Sci Transl Med. 2020. PMID: 32967973
Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma.
Ruiz-Pérez MV, Sainero-Alcolado L, Oliynyk G, Matuschek I, Balboni N, Ubhayasekera SJKA, Snaebjornsson MT, Makowski K, Aaltonen K, Bexell D, Serra D, Nilsson R, Bergquist J, Schulze A, Arsenian-Henriksson M. Ruiz-Pérez MV, et al. Among authors: bexell d. iScience. 2021 Feb 1;24(2):102128. doi: 10.1016/j.isci.2021.102128. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659885 Free PMC article.
Anti-tumor effects of rigosertib in high-risk neuroblastoma.
Radke K, Hansson K, Sjölund J, Wolska M, Karlsson J, Esfandyari J, Pietras K, Aaltonen K, Gisselsson D, Bexell D. Radke K, et al. Among authors: bexell d. Transl Oncol. 2021 Aug;14(8):101149. doi: 10.1016/j.tranon.2021.101149. Epub 2021 Jun 9. Transl Oncol. 2021. PMID: 34118691 Free PMC article.
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis.
Grigoryan A, Zacharaki D, Balhuizen A, Côme CR, Garcia AG, Hidalgo Gil D, Frank AK, Aaltonen K, Mañas A, Esfandyari J, Kjellman P, Englund E, Rodriguez C, Sime W, Massoumi R, Kalantari N, Prithiviraj S, Li Y, Dupard SJ, Isaksson H, Madsen CD, Porse BT, Bexell D, Bourgine PE. Grigoryan A, et al. Among authors: bexell d. Sci Transl Med. 2022 Oct 12;14(666):eabm6391. doi: 10.1126/scitranslmed.abm6391. Epub 2022 Oct 12. Sci Transl Med. 2022. PMID: 36223446
Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance.
Mañas A, Aaltonen K, Andersson N, Hansson K, Adamska A, Seger A, Yasui H, van den Bos H, Radke K, Esfandyari J, Bhave MS, Karlsson J, Spierings D, Foijer F, Gisselsson D, Bexell D. Mañas A, et al. Among authors: bexell d. Sci Adv. 2022 Oct 28;8(43):eabq4617. doi: 10.1126/sciadv.abq4617. Epub 2022 Oct 28. Sci Adv. 2022. PMID: 36306349 Free PMC article.
43 results