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The drug-induced phenotypic landscape of colorectal cancer organoids.
Betge J, Rindtorff N, Sauer J, Rauscher B, Dingert C, Gaitantzi H, Herweck F, Srour-Mhanna K, Miersch T, Valentini E, Boonekamp KE, Hauber V, Gutting T, Frank L, Belle S, Gaiser T, Buchholz I, Jesenofsky R, Härtel N, Zhan T, Fischer B, Breitkopf-Heinlein K, Burgermeister E, Ebert MP, Boutros M. Betge J, et al. Nat Commun. 2022 Jun 6;13(1):3135. doi: 10.1038/s41467-022-30722-9. Nat Commun. 2022. PMID: 35668108 Free PMC article.
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.
Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler RS, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M. Zhan T, et al. Among authors: betge j. Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0. Nat Commun. 2019. PMID: 31097693 Free PMC article.
CRISPR/Cas9 for cancer research and therapy.
Zhan T, Rindtorff N, Betge J, Ebert MP, Boutros M. Zhan T, et al. Among authors: betge j. Semin Cancer Biol. 2019 Apr;55:106-119. doi: 10.1016/j.semcancer.2018.04.001. Epub 2018 Apr 16. Semin Cancer Biol. 2019. PMID: 29673923 Free article. Review.
Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A.
Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, Betge J, Härtel N, Kather JN, Weis CA, Gaiser T, Marx A, Weiss C, Hofheinz R, Miller IS, Loupakis F, Lenz HJ, Byrne AT, Ebert MP. Burgermeister E, et al. Among authors: betge j. EBioMedicine. 2019 Jul;45:139-154. doi: 10.1016/j.ebiom.2019.07.004. Epub 2019 Jul 9. EBioMedicine. 2019. PMID: 31300350 Free PMC article.
PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells.
Gutting T, Hauber V, Pahl J, Klapproth K, Wu W, Dobrota I, Herweck F, Reichling J, Helm L, Schroeder T, Li B, Weidner P, Zhan T, Eckardt M, Betge J, Belle S, Sticht C, Gaiser T, Boutros M, Ebert MPA, Cerwenka A, Burgermeister E. Gutting T, et al. Among authors: betge j. Oncoimmunology. 2021 May 5;10(1):1906500. doi: 10.1080/2162402X.2021.1906500. Oncoimmunology. 2021. PMID: 34026331 Free PMC article.
47 results