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Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain.
Brouillette RL, Besserer-Offroy É, Mona CE, Chartier M, Lavenus S, Sousbie M, Belleville K, Longpré JM, Marsault É, Grandbois M, Sarret P. Brouillette RL, et al. Among authors: besserer offroy e. Pharmacol Res. 2020 May;155:104750. doi: 10.1016/j.phrs.2020.104750. Epub 2020 Mar 6. Pharmacol Res. 2020. PMID: 32151680
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog.
Tétreault P, Besserer-Offroy É, Brouillette RL, René A, Murza A, Fanelli R, Kirby K, Parent AJ, Dubuc I, Beaudet N, Côté J, Longpré JM, Martinez J, Cavelier F, Sarret P. Tétreault P, et al. Among authors: besserer offroy e. Eur J Pharmacol. 2020 Sep 5;882:173174. doi: 10.1016/j.ejphar.2020.173174. Epub 2020 Jun 10. Eur J Pharmacol. 2020. PMID: 32534076
Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2.
Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpré JM, Runyon SP, Decker AM, Gilmour BP, Sarret P. Thomas JB, et al. ACS Chem Neurosci. 2016 Sep 21;7(9):1225-31. doi: 10.1021/acschemneuro.6b00097. Epub 2016 Jul 13. ACS Chem Neurosci. 2016. PMID: 27359371
28 results