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Page 1
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.
Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, Pelullo M, Palermo R, Canettieri G, Talora C, d'Amati G, Bellavia D, Screpanti I, Checquolo S. Giuli MV, et al. Among authors: besharat zm. Oncogenesis. 2020 Oct 18;9(10):93. doi: 10.1038/s41389-020-00279-7. Oncogenesis. 2020. PMID: 33071287 Free PMC article.
Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL.
Pelullo M, Quaranta R, Talora C, Checquolo S, Cialfi S, Felli MP, te Kronnie G, Borga C, Besharat ZM, Palermo R, Di Marcotullio L, Capobianco AJ, Gulino A, Screpanti I, Bellavia D. Pelullo M, et al. Among authors: besharat zm. Neoplasia. 2014 Dec;16(12):1007-17. doi: 10.1016/j.neo.2014.10.004. Neoplasia. 2014. PMID: 25499214 Free PMC article.
Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.
Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, Besharat ZM, Nicoletti C, Siebel CW, Choy L, Rustighi A, Sal GD, Screpanti I, Checquolo S. Franciosa G, et al. Among authors: besharat zm. Oncogene. 2016 Sep 8;35(36):4741-51. doi: 10.1038/onc.2016.5. Epub 2016 Feb 15. Oncogene. 2016. PMID: 26876201 Free PMC article.
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma.
Po A, Silvano M, Miele E, Capalbo C, Eramo A, Salvati V, Todaro M, Besharat ZM, Catanzaro G, Cucchi D, Coni S, Di Marcotullio L, Canettieri G, Vacca A, Stassi G, De Smaele E, Tartaglia M, Screpanti I, De Maria R, Ferretti E. Po A, et al. Among authors: besharat zm. Oncogene. 2017 Aug 10;36(32):4641-4652. doi: 10.1038/onc.2017.91. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368412 Free PMC article.
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A, Cucchi D, Abballe L, Besharat ZM, Catanzaro G, Infante P, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I, Locatelli F, Ferretti E. Miele E, et al. Among authors: besharat zm. BMC Cancer. 2017 Jul 17;17(1):488. doi: 10.1186/s12885-017-3477-0. BMC Cancer. 2017. PMID: 28716052 Free PMC article.
Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs).
Catanzaro G, Sabato C, Russo M, Rosa A, Abballe L, Besharat ZM, Po A, Miele E, Bellavia D, Chiacchiarini M, Gessi M, Peruzzi G, Napolitano M, Antonelli M, Mastronuzzi A, Giangaspero F, Locatelli F, Screpanti I, Vacca A, Ferretti E. Catanzaro G, et al. Among authors: besharat zm. Int J Mol Sci. 2017 Dec 17;18(12):2742. doi: 10.3390/ijms18122742. Int J Mol Sci. 2017. PMID: 29258209 Free PMC article.
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.
Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, Maroder M, Talora C, Capalbo C, Bellavia D, Checquolo S. Diluvio G, et al. Among authors: besharat zm. Oncogenesis. 2018 May 25;7(5):42. doi: 10.1038/s41389-018-0051-9. Oncogenesis. 2018. PMID: 29795369 Free PMC article.
Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance.
Pelullo M, Nardozza F, Zema S, Quaranta R, Nicoletti C, Besharat ZM, Felli MP, Cerbelli B, d'Amati G, Palermo R, Capalbo C, Talora C, Di Marcotullio L, Giannini G, Checquolo S, Screpanti I, Bellavia D. Pelullo M, et al. Among authors: besharat zm. Cancer Res. 2019 Nov 1;79(21):5575-5586. doi: 10.1158/0008-5472.CAN-19-0145. Epub 2019 Sep 10. Cancer Res. 2019. PMID: 31506332
Downregulation of miR-326 and its host gene β-arrestin1 induces pro-survival activity of E2F1 and promotes medulloblastoma growth.
Miele E, Po A, Mastronuzzi A, Carai A, Besharat ZM, Pediconi N, Abballe L, Catanzaro G, Sabato C, De Smaele E, Canettieri G, Di Marcotullio L, Vacca A, Mai A, Levrero M, Pfister SM, Kool M, Giangaspero F, Locatelli F, Ferretti E. Miele E, et al. Among authors: besharat zm. Mol Oncol. 2021 Feb;15(2):523-542. doi: 10.1002/1878-0261.12800. Epub 2020 Dec 31. Mol Oncol. 2021. PMID: 32920979 Free PMC article.
52 results