Besche HC - Search Results

1

Cancer vulnerabilities unveiled by genomic loss.

Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC. Nijhawan D, et al. Among authors: besche hc. Cell. 2012 Aug 17;150(4):842-54. doi: 10.1016/j.cell.2012.07.023. Cell. 2012. PMID: 22901813 Free PMC article.

2

Getting to first base in proteasome assembly.

Besche HC, Peth A, Goldberg AL. Besche HC, et al. Cell. 2009 Jul 10;138(1):25-8. doi: 10.1016/j.cell.2009.06.035. Cell. 2009. PMID: 19596233 Free PMC article. Review.

3

Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening.

Peth A, Besche HC, Goldberg AL. Peth A, et al. Among authors: besche hc. Mol Cell. 2009 Dec 11;36(5):794-804. doi: 10.1016/j.molcel.2009.11.015. Mol Cell. 2009. PMID: 20005843 Free PMC article.

4

Affinity purification of mammalian 26S proteasomes using an ubiquitin-like domain.

Besche HC, Goldberg AL. Besche HC, et al. Methods Mol Biol. 2012;832:423-32. doi: 10.1007/978-1-61779-474-2_29. Methods Mol Biol. 2012. PMID: 22350902

5

Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins.

Besche HC, Haas W, Gygi SP, Goldberg AL. Besche HC, et al. Biochemistry. 2009 Mar 24;48(11):2538-49. doi: 10.1021/bi802198q. Biochemistry. 2009. PMID: 19182904 Free PMC article.

6

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

Besche HC, Sha Z, Kukushkin NV, Peth A, Hock EM, Kim W, Gygi S, Gutierrez JA, Liao H, Dick L, Goldberg AL. Besche HC, et al. EMBO J. 2014 May 16;33(10):1159-76. doi: 10.1002/embj.201386906. Epub 2014 May 8. EMBO J. 2014. PMID: 24811749 Free PMC article.

7

Characterization of the Brain 26S Proteasome and its Interacting Proteins.

Tai HC, Besche H, Goldberg AL, Schuman EM. Tai HC, et al. Among authors: besche h. Front Mol Neurosci. 2010 May 21;3:12. doi: 10.3389/fnmol.2010.00012. eCollection 2010. Front Mol Neurosci. 2010. PMID: 20717473 Free PMC article.

8

Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway.

Altun M, Besche HC, Overkleeft HS, Piccirillo R, Edelmann MJ, Kessler BM, Goldberg AL, Ulfhake B. Altun M, et al. Among authors: besche hc. J Biol Chem. 2010 Dec 17;285(51):39597-608. doi: 10.1074/jbc.M110.129718. Epub 2010 Oct 12. J Biol Chem. 2010. PMID: 20940294 Free PMC article.

9

The Thermoplasma acidophilum Lon protease has a Ser-Lys dyad active site.

Besche H, Zwickl P. Besche H, et al. Eur J Biochem. 2004 Nov;271(22):4361-5. doi: 10.1111/j.1432-1033.2004.04421.x. Eur J Biochem. 2004. PMID: 15560777 Free article.

10

Mutational analysis of conserved AAA+ residues in the archaeal Lon protease from Thermoplasma acidophilum.

Besche H, Tamura N, Tamura T, Zwickl P. Besche H, et al. FEBS Lett. 2004 Sep 10;574(1-3):161-6. doi: 10.1016/j.febslet.2004.08.021. FEBS Lett. 2004. PMID: 15358558 Free article.

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