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Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.
Zenaro E, Pietronigro E, Della Bianca V, Piacentino G, Marongiu L, Budui S, Turano E, Rossi B, Angiari S, Dusi S, Montresor A, Carlucci T, Nanì S, Tosadori G, Calciano L, Catalucci D, Berton G, Bonetti B, Constantin G. Zenaro E, et al. Among authors: berton g. Nat Med. 2015 Aug;21(8):880-6. doi: 10.1038/nm.3913. Epub 2015 Jul 27. Nat Med. 2015. PMID: 26214837
The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in sustained adhesion.
Giagulli C, Ottoboni L, Caveggion E, Rossi B, Lowell C, Constantin G, Laudanna C, Berton G. Giagulli C, et al. Among authors: berton g. J Immunol. 2006 Jul 1;177(1):604-11. doi: 10.4049/jimmunol.177.1.604. J Immunol. 2006. PMID: 16785558 Free article.
Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha and interleukin-8 mRNA in human neutrophils. Evidence for a role of L-selectin as a signaling molecule.
Laudanna C, Constantin G, Baron P, Scarpini E, Scarlato G, Cabrini G, Dechecchi C, Rossi F, Cassatella MA, Berton G. Laudanna C, et al. Among authors: berton g. J Biol Chem. 1994 Feb 11;269(6):4021-6. J Biol Chem. 1994. PMID: 7508438 Free article.
171 results