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Page 1
(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.
Ismaili L, Monnin J, Etievant A, Arribas RL, Viejo L, Refouvelet B, Soukup O, Janockova J, Hepnarova V, Korabecny J, Kucera T, Jun D, Andrys R, Musilek K, Baguet A, García-Frutos EM, De Simone A, Andrisano V, Bartolini M, de Los Ríos C, Marco-Contelles J, Haffen E. Ismaili L, et al. Among authors: refouvelet b. ACS Chem Neurosci. 2021 Apr 21;12(8):1328-1342. doi: 10.1021/acschemneuro.0c00803. Epub 2021 Apr 2. ACS Chem Neurosci. 2021. PMID: 33797877
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Bautista-Aguilera ÓM, Ismaili L, Chioua M, Andrys R, Schmidt M, Bzonek P, Martínez-Grau MÁ, Beadle CD, Vetman T, López-Muñoz F, Iriepa I, Refouvelet B, Musilek K, Marco-Contelles J. Bautista-Aguilera ÓM, et al. Among authors: refouvelet b. Int J Mol Sci. 2020 May 30;21(11):3913. doi: 10.3390/ijms21113913. Int J Mol Sci. 2020. PMID: 32486316 Free PMC article.
Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels.
Pachòn Angona I, Daniel S, Martin H, Bonet A, Wnorowski A, Maj M, Jóźwiak K, Silva TB, Refouvelet B, Borges F, Marco-Contelles J, Ismaili L. Pachòn Angona I, et al. Among authors: refouvelet b. Molecules. 2020 Mar 14;25(6):1329. doi: 10.3390/molecules25061329. Molecules. 2020. PMID: 32183349 Free PMC article.
Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy.
Pachón-Angona I, Refouvelet B, Andrýs R, Martin H, Luzet V, Iriepa I, Moraleda I, Diez-Iriepa D, Oset-Gasque MJ, Marco-Contelles J, Musilek K, Ismaili L. Pachón-Angona I, et al. Among authors: refouvelet b. J Enzyme Inhib Med Chem. 2019 Dec;34(1):479-489. doi: 10.1080/14756366.2018.1545766. J Enzyme Inhib Med Chem. 2019. PMID: 30712420 Free PMC article.
25 results