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A three-gene DNA methylation biomarker accurately classifies early stage prostate cancer.
Patel PG, Wessel T, Kawashima A, Okello JBA, Jamaspishvili T, Guérard KP, Lee L, Lee AY, How NE, Dion D, Scarlata E, Jackson CL, Boursalie S, Sack T, Dunn R, Moussa M, Mackie/ K, Ellis A, Marra E, Chin J, Siddiqui K, Hetou K, Pickard LA, Arthur-Hayward V, Bauman G, Chevalier S, Brimo F, Boutros PC, Lapointe PhD J, Bartlett JMS, Gooding RJ, Berman DM. Patel PG, et al. Among authors: berman dm. Prostate. 2019 Oct;79(14):1705-1714. doi: 10.1002/pros.23895. Epub 2019 Aug 21. Prostate. 2019. PMID: 31433512
PTEN-deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells.
Vidotto T, Saggioro FP, Jamaspishvili T, Chesca DL, Picanço de Albuquerque CG, Reis RB, Graham CH, Berman DM, Siemens DR, Squire JA, Koti M. Vidotto T, et al. Among authors: berman dm. Prostate. 2019 Jun;79(9):969-979. doi: 10.1002/pros.23808. Epub 2019 Apr 18. Prostate. 2019. PMID: 30999388
Clinical implications of PTEN loss in prostate cancer.
Jamaspishvili T, Berman DM, Ross AE, Scher HI, De Marzo AM, Squire JA, Lotan TL. Jamaspishvili T, et al. Among authors: berman dm. Nat Rev Urol. 2018 Apr;15(4):222-234. doi: 10.1038/nrurol.2018.9. Epub 2018 Feb 20. Nat Rev Urol. 2018. PMID: 29460925 Free PMC article. Review.
209 results