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Page 1
Histamine H3 receptor as a drug discovery target.
Berlin M, Boyce CW, Ruiz Mde L. Berlin M, et al. J Med Chem. 2011 Jan 13;54(1):26-53. doi: 10.1021/jm100064d. Epub 2010 Nov 9. J Med Chem. 2011. PMID: 21062081 Review. No abstract available.
Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists.
Berlin M, Ting PC, Vaccaro WD, Aslanian R, McCormick KD, Lee JF, Albanese MM, Mutahi MW, Piwinski JJ, Shih NY, Duguma L, Solomon DM, Zhou W, Sher R, Favreau L, Bryant M, Korfmacher WA, Nardo C, West RE Jr, Anthes JC, Williams SM, Wu RL, Susan She H, Rivelli MA, Corboz MR, Hey JA. Berlin M, et al. Bioorg Med Chem Lett. 2006 Feb 15;16(4):989-94. doi: 10.1016/j.bmcl.2005.10.087. Epub 2005 Nov 15. Bioorg Med Chem Lett. 2006. PMID: 16297617
Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.
Vaccaro WD, Sher R, Berlin M, Shih NY, Aslanian R, Schwerdt JH, McCormick KD, Piwinski JJ, West RE Jr, Anthes JC, Williams SM, Wu RL, She HS, Rivelli MA, Mutter JC, Corboz MR, Hey JA, Favreau L. Vaccaro WD, et al. Among authors: berlin m. Bioorg Med Chem Lett. 2006 Jan 15;16(2):395-9. doi: 10.1016/j.bmcl.2005.09.076. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246552
Steroidal C-21 heteroaryl thioethers (Part 2): discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids).
Biju P, McCormick K, Aslanian R, Berlin M, Solomon D, Wang H, Lee YJ, Bitar R, Prelusky D, McLeod R, Jia Y, Fernandez X, Eckel S, House A, Lieber G, Jimenez J, Kelly G, Chapman R, Phillips J, Anthes J. Biju P, et al. Among authors: berlin m. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1086-90. doi: 10.1016/j.bmcl.2011.11.120. Epub 2011 Dec 7. Bioorg Med Chem Lett. 2012. PMID: 22197391
Identification of a novel, orally bioavailable histamine H(3) receptor antagonist based on the 4-benzyl-(1H-imidazol-4-yl) template.
Aslanian R, Mutahi MW, Shih NY, McCormick KD, Piwinski JJ, Ting PC, Albanese MM, Berlin MY, Zhu X, Wong SC, Rosenblum SB, Jiang Y, West R, She S, Williams SM, Bryant M, Hey JA. Aslanian R, et al. Among authors: berlin my. Bioorg Med Chem Lett. 2002 Mar 25;12(6):937-41. doi: 10.1016/s0960-894x(02)00055-0. Bioorg Med Chem Lett. 2002. PMID: 11958998
Steroidal C-21 mercapto derivatives as dissociated steroids: discovery of an inhaled dissociated steroid.
Biju P, McCormick K, Aslanian R, Berlin M, Solomon D, Chapman R, McLeod R, Prelusky D, Eckel S, Kelly G, Natiello M, House A, Fernandez X, Bitar R, Phillips J, Anthes J. Biju P, et al. Among authors: berlin m. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6343-7. doi: 10.1016/j.bmcl.2011.08.108. Epub 2011 Aug 31. Bioorg Med Chem Lett. 2011. PMID: 21944381
240 results