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Clinical trials of self-replicating RNA-based cancer vaccines.
Morse MA, Crosby EJ, Force J, Osada T, Hobeika AC, Hartman ZC, Berglund P, Smith J, Lyerly HK. Morse MA, et al. Among authors: berglund p. Cancer Gene Ther. 2023 Jun;30(6):803-811. doi: 10.1038/s41417-023-00587-1. Epub 2023 Feb 10. Cancer Gene Ther. 2023. PMID: 36765179 Free PMC article. Review.
An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer.
Morse MA, Hobeika AC, Osada T, Berglund P, Hubby B, Negri S, Niedzwiecki D, Devi GR, Burnett BK, Clay TM, Smith J, Lyerly HK. Morse MA, et al. Among authors: berglund p. J Clin Invest. 2010 Sep;120(9):3234-41. doi: 10.1172/JCI42672. Epub 2010 Aug 2. J Clin Invest. 2010. PMID: 20679728 Free PMC article.
Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio.
Crosby EJ, Hobeika AC, Niedzwiecki D, Rushing C, Hsu D, Berglund P, Smith J, Osada T, Gwin Iii WR, Hartman ZC, Morse MA, Lyerly HK. Crosby EJ, et al. Among authors: berglund p. J Immunother Cancer. 2020 Nov;8(2):e001662. doi: 10.1136/jitc-2020-001662. J Immunother Cancer. 2020. PMID: 33177177 Free PMC article.
Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects.
Osada T, Berglund P, Morse MA, Hubby B, Lewis W, Niedzwiecki D, Yang XY, Hobeika A, Burnett B, Devi GR, Clay TM, Smith J, Kim Lyerly H. Osada T, et al. Among authors: berglund p. Cancer Immunol Immunother. 2012 Nov;61(11):1941-51. doi: 10.1007/s00262-012-1248-y. Epub 2012 Apr 10. Cancer Immunol Immunother. 2012. PMID: 22488274 Free PMC article.
Development and preclinical evaluation of an alphavirus replicon vaccine for influenza.
Hubby B, Talarico T, Maughan M, Reap EA, Berglund P, Kamrud KI, Copp L, Lewis W, Cecil C, Norberg P, Wagner J, Watson A, Negri S, Burnett BK, Graham A, Smith JF, Chulay JD. Hubby B, et al. Among authors: berglund p. Vaccine. 2007 Nov 23;25(48):8180-9. doi: 10.1016/j.vaccine.2007.09.038. Epub 2007 Oct 5. Vaccine. 2007. PMID: 17961878 Free PMC article.
The Importance of RNA-Based Vaccines in the Fight against COVID-19: An Overview.
Machado BAS, Hodel KVS, Fonseca LMDS, Mascarenhas LAB, Andrade LPCDS, Rocha VPC, Soares MBP, Berglund P, Duthie MS, Reed SG, Badaró R. Machado BAS, et al. Among authors: berglund p. Vaccines (Basel). 2021 Nov 17;9(11):1345. doi: 10.3390/vaccines9111345. Vaccines (Basel). 2021. PMID: 34835276 Free PMC article. Review.
Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates.
Erasmus JH, Khandhar AP, Walls AC, Hemann EA, O'Connor MA, Murapa P, Archer J, Leventhal S, Fuller J, Lewis T, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Among authors: berglund p. bioRxiv [Preprint]. 2020 May 28:2020.05.28.121640. doi: 10.1101/2020.05.28.121640. bioRxiv. 2020. PMID: 32511417 Free PMC article. Preprint.
RNA replicon delivery via lipid-complexed PRINT protein particles.
Xu J, Luft JC, Yi X, Tian S, Owens G, Wang J, Johnson A, Berglund P, Smith J, Napier ME, DeSimone JM. Xu J, et al. Among authors: berglund p. Mol Pharm. 2013 Sep 3;10(9):3366-74. doi: 10.1021/mp400190z. Epub 2013 Aug 21. Mol Pharm. 2013. PMID: 23924216 Free PMC article.
184 results