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Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018.
Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kuebler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT. Olschewski A, et al. Among authors: berghausen em. Int J Cardiol. 2018 Dec 1;272S:4-10. doi: 10.1016/j.ijcard.2018.09.070. Epub 2018 Sep 20. Int J Cardiol. 2018. PMID: 30314839 Review.
[Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016].
Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kübler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT. Olschewski A, et al. Among authors: berghausen em. Dtsch Med Wochenschr. 2016 Oct;141(S 01):S4-S9. doi: 10.1055/s-0042-114520. Epub 2016 Oct 19. Dtsch Med Wochenschr. 2016. PMID: 27760444 German.
Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.
Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi GA, Aytekin M, Dweik RA, Hennigs JK, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph TK, Hazen SL, Klose H, Schermuly RT, Rudolph V, Baldus S. Klinke A, et al. JCI Insight. 2018 Jun 7;3(11):e97530. doi: 10.1172/jci.insight.97530. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875311 Free PMC article.
Role of Src tyrosine kinases in experimental pulmonary hypertension.
Pullamsetti SS, Berghausen EM, Dabral S, Tretyn A, Butrous E, Savai R, Butrous G, Dahal BK, Brandes RP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Rosenkranz S, Schermuly RT. Pullamsetti SS, et al. Among authors: berghausen em. Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1354-65. doi: 10.1161/ATVBAHA.112.248500. Epub 2012 Apr 19. Arterioscler Thromb Vasc Biol. 2012. PMID: 22516066
Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents.
Berghausen EM, Janssen W, Vantler M, Gnatzy-Feik LL, Krause M, Behringer A, Joseph C, Zierden M, Freyhaus HT, Klinke A, Baldus S, Alcazar MA, Savai R, Pullamsetti SS, Wong DW, Boor P, Zhao JJ, Schermuly RT, Rosenkranz S. Berghausen EM, et al. J Clin Invest. 2021 Oct 1;131(19):e136939. doi: 10.1172/JCI136939. J Clin Invest. 2021. PMID: 34596056 Free PMC article.
Genetic Ablation of PDGF-Dependent Signaling Pathways Abolishes Vascular Remodeling and Experimental Pulmonary Hypertension.
Ten Freyhaus H, Berghausen EM, Janssen W, Leuchs M, Zierden M, Murmann K, Klinke A, Vantler M, Caglayan E, Kramer T, Baldus S, Schermuly RT, Tallquist MD, Rosenkranz S. Ten Freyhaus H, et al. Among authors: berghausen em. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1236-45. doi: 10.1161/ATVBAHA.114.304864. Epub 2015 Mar 5. Arterioscler Thromb Vasc Biol. 2015. PMID: 25745058 Free PMC article.
Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases.
ten Freyhaus H, Dagnell M, Leuchs M, Vantler M, Berghausen EM, Caglayan E, Weissmann N, Dahal BK, Schermuly RT, Ostman A, Kappert K, Rosenkranz S. ten Freyhaus H, et al. Among authors: berghausen em. Am J Respir Crit Care Med. 2011 Apr 15;183(8):1092-102. doi: 10.1164/rccm.200911-1663OC. Epub 2010 Dec 22. Am J Respir Crit Care Med. 2011. PMID: 21177885
Imatinib mesylate for the treatment of pulmonary arterial hypertension.
ten Freyhaus H, Dumitrescu D, Berghausen E, Vantler M, Caglayan E, Rosenkranz S. ten Freyhaus H, et al. Expert Opin Investig Drugs. 2012 Jan;21(1):119-34. doi: 10.1517/13543784.2012.632408. Epub 2011 Nov 11. Expert Opin Investig Drugs. 2012. PMID: 22074410 Review.
16 results