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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure.
Beltra JC, Abdel-Hakeem MS, Manne S, Zhang Z, Huang H, Kurachi M, Su L, Picton L, Ngiow SF, Muroyama Y, Casella V, Huang YJ, Giles JR, Mathew D, Belman J, Klapholz M, Decaluwe H, Huang AC, Berger SL, Garcia KC, Wherry EJ. Beltra JC, et al. Among authors: berger sl. Immunity. 2023 Dec 12;56(12):2699-2718.e11. doi: 10.1016/j.immuni.2023.11.005. Immunity. 2023. PMID: 38091951
Loss of epigenetic information as a cause of mammalian aging.
Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA. Yang JH, et al. Among authors: berger sl. Cell. 2024 Feb 29;187(5):1312-1313. doi: 10.1016/j.cell.2024.01.049. Cell. 2024. PMID: 38428398 No abstract available.
Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer.
Alexander KA, Yu R, Skuli N, Coffey NJ, Nguyen S, Faunce C, Huang H, Dardani IP, Good AL, Lim J, Li C, Biddle N, Joyce EF, Raj A, Lee D, Keith B, Simon MC, Berger SL. Alexander KA, et al. Among authors: berger sl. bioRxiv [Preprint]. 2023 Sep 16:2023.09.14.557228. doi: 10.1101/2023.09.14.557228. bioRxiv. 2023. PMID: 37745397 Free PMC article. Preprint.
311 results