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Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase.
Fuertig R, Azzinnari D, Bergamini G, Cathomas F, Sigrist H, Seifritz E, Vavassori S, Luippold A, Hengerer B, Ceci A, Pryce CR. Fuertig R, et al. Among authors: bergamini g. Brain Behav Immun. 2016 May;54:59-72. doi: 10.1016/j.bbi.2015.12.020. Epub 2015 Dec 24. Brain Behav Immun. 2016. PMID: 26724575
Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice.
Cathomas F, Azzinnari D, Bergamini G, Sigrist H, Buerge M, Hoop V, Wicki B, Goetze L, Soares S, Kukelova D, Seifritz E, Goebbels S, Nave KA, Ghandour MS, Seoighe C, Hildebrandt T, Leparc G, Klein H, Stupka E, Hengerer B, Pryce CR. Cathomas F, et al. Among authors: bergamini g. Genes Brain Behav. 2019 Jan;18(1):e12475. doi: 10.1111/gbb.12475. Epub 2018 Apr 17. Genes Brain Behav. 2019. PMID: 29566304 Free article.
Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice.
Bergamini G, Mechtersheimer J, Azzinnari D, Sigrist H, Buerge M, Dallmann R, Freije R, Kouraki A, Opacka-Juffry J, Seifritz E, Ferger B, Suter T, Pryce CR. Bergamini G, et al. Neurobiol Stress. 2018 Feb 2;8:42-56. doi: 10.1016/j.ynstr.2018.01.004. eCollection 2018 Feb. Neurobiol Stress. 2018. PMID: 29888303 Free PMC article.
Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice.
Madur L, Ineichen C, Bergamini G, Greter A, Poggi G, Cuomo-Haymour N, Sigrist H, Sych Y, Paterna JC, Bornemann KD, Viollet C, Fernandez-Albert F, Alanis-Lobato G, Hengerer B, Pryce CR. Madur L, et al. Among authors: bergamini g. Commun Biol. 2023 Apr 15;6(1):422. doi: 10.1038/s42003-023-04811-4. Commun Biol. 2023. PMID: 37061616 Free PMC article.
204 results