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Novel analogues of istaroxime, a potent inhibitor of Na+,K+-ATPase: synthesis and structure-activity relationship.
J Med Chem. 2008 Aug 14;51(15):4601-8. doi: 10.1021/jm800257s. Epub 2008 Jul 19.
J Med Chem. 2008.
PMID: 18637667
Synthesis and inotropic activity of 1-(O-aminoalkyloximes) of perhydroindene derivatives as simplified digitalis-like compounds acting on the Na(+),K(+)-ATPase.
Cerri A, Almirante N, Barassi P, Benicchio A, De Munari S, Marazzi G, Molinari I, Serra F, Melloni P.
Cerri A, et al. Among authors: benicchio a.
J Med Chem. 2002 Jan 3;45(1):189-207. doi: 10.1021/jm011001k.
J Med Chem. 2002.
PMID: 11754591
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Novel analogues of Istaroxime, a potent inhibitor of Na(+),K(+)-ATPase: Synthesis, structure-activity relationship and 3D-quantitative structure-activity relationship of derivatives at position 6 on the androstane scaffold.
Gobbini M, Armaroli S, Banfi L, Benicchio A, Carzana G, Ferrari P, Giacalone G, Marazzi G, Moro B, Micheletti R, Sputore S, Torri M, Zappavigna MP, Cerri A.
Gobbini M, et al. Among authors: benicchio a.
Bioorg Med Chem. 2010 Jun 15;18(12):4275-99. doi: 10.1016/j.bmc.2010.04.095. Epub 2010 May 20.
Bioorg Med Chem. 2010.
PMID: 20494582
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17beta-O-Aminoalkyloximes of 5beta-androstane-3beta,14beta-diol with digitalis-like activity: synthesis, cardiotonic activity, structure-activity relationships, and molecular modeling of the Na(+),K(+)-ATPase receptor.
Cerri A, Almirante N, Barassi P, Benicchio A, Fedrizzi G, Ferrari P, Micheletti R, Quadri L, Ragg E, Rossi R, Santagostino M, Schiavone A, Serra F, Zappavigna MP, Melloni P.
Cerri A, et al. Among authors: benicchio a.
J Med Chem. 2000 Jun 15;43(12):2332-49. doi: 10.1021/jm990627w.
J Med Chem. 2000.
PMID: 10882359
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Digitalis-like compounds: synthesis and biological evaluation of seco-D and D-homo derivatives.
Gobbini M, Benicchio A, Marazzi G, Padoani G, Torri M, Melloni P.
Gobbini M, et al. Among authors: benicchio a.
Steroids. 1996 Oct;61(10):572-82. doi: 10.1016/s0039-128x(96)00117-1.
Steroids. 1996.
PMID: 8910970
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