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T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10.
Ravi VM, Neidert N, Will P, Joseph K, Maier JP, Kückelhaus J, Vollmer L, Goeldner JM, Behringer SP, Scherer F, Boerries M, Follo M, Weiss T, Delev D, Kernbach J, Franco P, Schallner N, Dierks C, Carro MS, Hofmann UG, Fung C, Sankowski R, Prinz M, Beck J, Salié H, Bengsch B, Schnell O, Heiland DH. Ravi VM, et al. Among authors: bengsch b. Nat Commun. 2022 Feb 17;13(1):925. doi: 10.1038/s41467-022-28523-1. Nat Commun. 2022. PMID: 35177622 Free PMC article.
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion.
Khan O, Giles JR, McDonald S, Manne S, Ngiow SF, Patel KP, Werner MT, Huang AC, Alexander KA, Wu JE, Attanasio J, Yan P, George SM, Bengsch B, Staupe RP, Donahue G, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Kaye J, Berger SL, Wherry EJ. Khan O, et al. Among authors: bengsch b. Nature. 2019 Jul;571(7764):211-218. doi: 10.1038/s41586-019-1325-x. Epub 2019 Jun 17. Nature. 2019. PMID: 31207603 Free PMC article.
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions.
Schwabenland M, Salié H, Tanevski J, Killmer S, Lago MS, Schlaak AE, Mayer L, Matschke J, Püschel K, Fitzek A, Ondruschka B, Mei HE, Boettler T, Neumann-Haefelin C, Hofmann M, Breithaupt A, Genc N, Stadelmann C, Saez-Rodriguez J, Bronsert P, Knobeloch KP, Blank T, Thimme R, Glatzel M, Prinz M, Bengsch B. Schwabenland M, et al. Among authors: bengsch b. Immunity. 2021 Jul 13;54(7):1594-1610.e11. doi: 10.1016/j.immuni.2021.06.002. Epub 2021 Jun 9. Immunity. 2021. PMID: 34174183 Free PMC article.
Imaging mass cytometry for high-dimensional tissue profiling in the eye.
Schlecht A, Boneva S, Salie H, Killmer S, Wolf J, Hajdu RI, Auw-Haedrich C, Agostini H, Reinhard T, Schlunck G, Bengsch B, Lange CA. Schlecht A, et al. Among authors: bengsch b. BMC Ophthalmol. 2021 Sep 20;21(1):338. doi: 10.1186/s12886-021-02099-8. BMC Ophthalmol. 2021. PMID: 34544377 Free PMC article.
T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma.
Barsch M, Salié H, Schlaak AE, Zhang Z, Hess M, Mayer LS, Tauber C, Otto-Mora P, Ohtani T, Nilsson T, Wischer L, Winkler F, Manne S, Rech A, Schmitt-Graeff A, Bronsert P, Hofmann M, Neumann-Haefelin C, Boettler T, Fichtner-Feigl S, van Boemmel F, Berg T, Rimassa L, Di Tommaso L, Saeed A, D'Alessio A, Pinato DJ, Bettinger D, Binder H, John Wherry E, Schultheiss M, Thimme R, Bengsch B. Barsch M, et al. Among authors: bengsch b. J Hepatol. 2022 Aug;77(2):397-409. doi: 10.1016/j.jhep.2022.02.032. Epub 2022 Apr 1. J Hepatol. 2022. PMID: 35367533
SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis.
Boettler T, Csernalabics B, Salié H, Luxenburger H, Wischer L, Salimi Alizei E, Zoldan K, Krimmel L, Bronsert P, Schwabenland M, Prinz M, Mogler C, Neumann-Haefelin C, Thimme R, Hofmann M, Bengsch B. Boettler T, et al. Among authors: bengsch b. J Hepatol. 2022 Sep;77(3):653-659. doi: 10.1016/j.jhep.2022.03.040. Epub 2022 Apr 21. J Hepatol. 2022. PMID: 35461912 Free PMC article.
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.
Ravi VM, Will P, Kueckelhaus J, Sun N, Joseph K, Salié H, Vollmer L, Kuliesiute U, von Ehr J, Benotmane JK, Neidert N, Follo M, Scherer F, Goeldner JM, Behringer SP, Franco P, Khiat M, Zhang J, Hofmann UG, Fung C, Ricklefs FL, Lamszus K, Boerries M, Ku M, Beck J, Sankowski R, Schwabenland M, Prinz M, Schüller U, Killmer S, Bengsch B, Walch AK, Delev D, Schnell O, Heiland DH. Ravi VM, et al. Among authors: bengsch b. Cancer Cell. 2022 Jun 13;40(6):639-655.e13. doi: 10.1016/j.ccell.2022.05.009. Cancer Cell. 2022. PMID: 35700707 Free article.
Exhaustion of CD39-Expressing CD8+ T Cells in Crohn's Disease Is Linked to Clinical Outcome.
Globig AM, Mayer LS, Heeg M, Andrieux G, Ku M, Otto-Mora P, Hipp AV, Zoldan K, Pattekar A, Rana N, Schell C, Boerries M, Hofmann M, Neumann-Haefelin C, Kuellmer A, Schmidt A, Boettler T, Tomov V, Thimme R, Hasselblatt P, Bengsch B. Globig AM, et al. Among authors: bengsch b. Gastroenterology. 2022 Oct;163(4):965-981.e31. doi: 10.1053/j.gastro.2022.06.045. Epub 2022 Jun 20. Gastroenterology. 2022. PMID: 35738329
COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation.
Reinscheid M, Luxenburger H, Karl V, Graeser A, Giese S, Ciminski K, Reeg DB, Oberhardt V, Roehlen N, Lang-Meli J, Heim K, Gross N, Baum C, Rieg S, Speer C, Emmerich F, Breisinger S, Steinmann D, Bengsch B, Boettler T, Kochs G, Schwemmle M, Thimme R, Neumann-Haefelin C, Hofmann M. Reinscheid M, et al. Among authors: bengsch b. Nat Commun. 2022 Aug 8;13(1):4631. doi: 10.1038/s41467-022-32324-x. Nat Commun. 2022. PMID: 35941157 Free PMC article.
100 results